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NCT07115069 · ClinicalTrials.gov registry record

Comparison of Body Composition Changes With Weight Loss Interventions

A clinical trial of Obesity, sponsored by Vanderbilt University Medical Center.

Recruiting
Registry status
60
Enrollment target
1
Study location

NCT07115069 is a study of Obesity that is actively recruiting participants, run by Vanderbilt University Medical Center. The registered enrollment target is 60 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07115069, a study of Obesity, is actively recruiting participants, sponsored by Vanderbilt University Medical Center.

RECRUITING
Registry status
60 participants
Enrollment target
1
Study location

Study Summary

This study is being done to compare the effects of a newer class of weight loss medications to weight loss surgery on the body's muscle, metabolism, and side effects over time. People with severe obesity often lose weight using either medications like GLP-1 receptor agonists (such as semaglutide or tirzepatide) or by having bariatric surgery, such as gastric bypass. While both approaches can lead to weight loss, they may affect the body in different ways. The investigators are inviting adult patients who are planning to either start one of these weight loss medications or undergo gastric bypass surgery to join this study. Participants will be asked to complete four body composition scans (called DXA scans) over the course of a year-at the beginning of the study and again at 3, 6, and 12 months. These scans will help us measure changes in fat and muscle. Participants will also complete surveys and provide information on side effects, such as nausea or fatigue, that may affect their eating or activity levels. The investigators' goal is to better understand how different weight loss treatments impact not just weight, but also muscle mass, energy levels, and side effects. This information may help doctors and patients choose the most appropriate treatment in the future.

Conditions Studied

Obesity

Interventions

  • DRUG GLP-1 receptor agonist
  • PROCEDURE Gastric Bypass Surgery (laparoscopic)
  • PROCEDURE Gastric Bypass Surgery (robotic)

Study Locations (1)

Tennessee

  • Vanderbilt University Medical Center - Nashville

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2025-08-09
Est. Completion 2027-01

Sponsor

Vanderbilt University Medical Center

677 total trials

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What the Registry Record Tells You About NCT07115069

The ClinicalTrials.gov registry entry for NCT07115069 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (93% lower). The listed sponsor is Vanderbilt University Medical Center, which has 677 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Obesity appearing as the primary indexed condition, and to 3 interventions - of which GLP-1 receptor agonist is the first listed.

NCT07115069 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.

Frequently Asked Questions

What is clinical trial NCT07115069 about?

NCT07115069 is a clinical study titled "Comparison of Body Composition Changes With Weight Loss Interventions". This study is being done to compare the effects of a newer class of weight loss medications to weight loss surgery on the body's muscle, metabolism, and side effects over time. People with severe obesity often lose weight using either medications like GLP-1 receptor agonists (such as semaglutide or ...

What is the current status of trial NCT07115069?

This trial is currently recruiting. The enrollment target is 60 participants. The study started on 2025-08-09. Estimated completion is 2027-01.

What conditions does trial NCT07115069 study?

This clinical trial studies the following conditions: Obesity.

What interventions are being tested in trial NCT07115069?

The interventions under investigation include: GLP-1 receptor agonist (DRUG), Gastric Bypass Surgery (laparoscopic) (PROCEDURE), Gastric Bypass Surgery (robotic) (PROCEDURE).

Who is sponsoring clinical trial NCT07115069?

This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07115069 being conducted?

This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.