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NCT07105826 · ClinicalTrials.gov registry record · NA

Impact of Prebiotic Sodas on Satiety and Metabolic Responses in Healthy Men

A NA study of Olipop and Poppi, sponsored by Texas Christian University.

Recruiting
Registry status
NA
Development phase
10
Enrollment target
1
Study location

NCT07105826: Recruiting NA study of Olipop and Poppi, sponsored by Texas Christian University.

NCT07105826 is a NA study of Olipop and Poppi that is actively recruiting participants, run by Texas Christian University. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07105826, a NA study of Olipop and Poppi, is actively recruiting participants, sponsored by Texas Christian University.

RECRUITING
Registry status
NA
Development phase
10 participants
Enrollment target
1
Study location

Study Summary

The study aims to study healthy men aged 18-40 to explore how different beverages affect hunger, blood sugar, insulin, and a hormone called GLP-1, which helps regulate appetite and blood sugar. The tested beverages include two prebiotic sodas (Olipop and Poppi), Diet Coke, and Coca-Cola Classic. What's the study about? It aims to understand how these drinks influence how full participants feel and how the body handles sugar and hormones compared to each other. This could help us learn more about how prebiotic drinks, which may support gut health, compare to regular sugary or diet sodas. What will participants do? Participants will visit our lab at TCU (Rickel Building, rooms 256/259) four times over four weeks, with each visit lasting about 2-2.5 hours. Participants will need to fast for 8-12 hours before each visit. Here's what happens: * First visit involves participants' consent, measurement of height and weight, and performing a finger-stick test to check blood sugar and HbA1C. Participants will also fill out questionnaires about health, diet, and beverage preferences. * Visits 2-4: In visit 2, a DEXA scan will be performed to assess body composition. In visits 2-4, participants will drink one of the four beverages (in a random order, served in an unlabeled black container to prevent drink identification). Other variables measured at these time points include blood pressure, fasting glucose, insulin, and GLP-1. Participants will also complete questionnaires about hunger and how the drink tastes. Each visit is spaced out by a week, and the total time commitment is about 10.5 hours. The study is expected to complete participant recruitment by December 10, 2025. Who can join? Ten healthy men aged 18-40 who don't have diabetes, heart disease, kidney or liver issues, or other specific health conditions. Participants shouldn't smoke, vape, or have certain dietary habits like intermittent fasting. Participants will be screened to confirm eligibility. What are th

Primary Outcome

The AUC of plasma glucose concentrations will be compared between the four conditions.

Interventions

  • OTHER Prebiotic Soda 1
  • OTHER Prebiotic Soda 2
  • OTHER Diet Soda
  • OTHER Regular Coke

Study Locations (1)

Texas

  • Texas Christian University - Fort Worth

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2025-08-04
Est. Completion 2025-12-10
Phase NA
Texas Christian University

26 total trials

What NCT07105826 shows while recruiting

NCT07105826 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 4 conditions, with Olipop appearing as the primary indexed condition, and to 4 interventions - of which Prebiotic Soda 1 is the first listed.

NCT07105826 reports a single indexed study location in Texas.

Frequently Asked Questions

What is clinical trial NCT07105826 about?

NCT07105826 is a clinical study titled "Impact of Prebiotic Sodas on Satiety and Metabolic Responses in Healthy Men". The study aims to study healthy men aged 18-40 to explore how different beverages affect hunger, blood sugar, insulin, and a hormone called GLP-1, which helps regulate appetite and blood sugar. The tested beverages include two prebiotic sodas (Olipop and Poppi), Diet Coke, and Coca-Cola Classic. Wh...

What is the current status of trial NCT07105826?

This trial is currently recruiting. It is a NA study. The enrollment target is 10 participants. The study started on 2025-08-04. Estimated completion is 2025-12-10.

What conditions does trial NCT07105826 study?

This clinical trial studies the following conditions: Olipop, Poppi, Coca Cola - Classic, Diet Coke.

What interventions are being tested in trial NCT07105826?

The interventions under investigation include: Prebiotic Soda 1 (OTHER), Prebiotic Soda 2 (OTHER), Diet Soda (OTHER), Regular Coke (OTHER).

Who is sponsoring clinical trial NCT07105826?

This trial is sponsored by Texas Christian University, which has 26 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07105826 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

How this trial's enrollment target compares

Where NCT07105826's enrollment target sits among peer trials

10 1927th of 2000 higher than 26 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07105826, the US trial registry maintained by the National Library of Medicine. NCT07105826 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.