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NCT07103941 · ClinicalTrials.gov registry record · NA
IOA Preventing Occlusal Changes With MAD Use
A NA study of Obstructive Sleep Apnea (OSA) and Snoring, sponsored by Isabel Moreno Hay.
- Recruiting
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT07103941: Recruiting NA study of Obstructive Sleep Apnea (OSA) and Snoring, sponsored by Isabel Moreno Hay.
NCT07103941 is a NA study of Obstructive Sleep Apnea (OSA) and Snoring that is actively recruiting participants, run by Isabel Moreno Hay. The registered enrollment target is 30 participants, below the 590-participant average among 12 other Obstructive Sleep Apnea (OSA) trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07103941, a NA study of Obstructive Sleep Apnea (OSA) and Snoring, is actively recruiting participants, sponsored by Isabel Moreno Hay.
- RECRUITING
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is evaluating two standard-of-care strategies used to prevent bite changes (occlusal changes) in patients treated with a Mandibular Advancement Device (MAD) for sleep-related breathing disorders such as obstructive sleep apnea (OSA). While MAD therapy is effective, it can lead to changes in how the teeth fit together, including the development of a posterior open bite. Participants in this study will be randomly assigned to one of two standard-of-care approaches: using an interocclusal aligner each morning after removing the MAD, or performing daily jaw exercises. Both methods aim to reduce the risk of occlusal changes. The study will follow participants over a 3-month period and includes dental evaluations, 3D oral scans, and short daily surveys. Findings from this research may help guide best practices for preserving occlusion during MAD therapy.
Primary Outcome
Recruitment will be measured by tracking the number of participants who agree to enroll in a randomized clinical trial comparing stretching exercises to the use of an interocclusal aligner (IOA).
Conditions Studied
Interventions
- BEHAVIORAL Exercise
- DEVICE AM Aligner
Study Locations (1)
Kentucky
- Orofacial Pain Center - University of Kentucky - Kentucky Clinic - Lexington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2025-11-17 |
| Est. Completion | 2026-04-30 |
| Phase | NA |
What NCT07103941 shows while recruiting
NCT07103941 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 590-participant average among 12 other Obstructive Sleep Apnea (OSA) trials with a reported enrollment target (95% lower).
The record links to 7 conditions, with Obstructive Sleep Apnea (OSA) appearing as the primary indexed condition, and to 2 interventions - of which Exercise is the first listed.
NCT07103941 reports a single indexed study location in Kentucky.
Frequently Asked Questions
What is clinical trial NCT07103941 about?
NCT07103941 is a clinical study titled "IOA Preventing Occlusal Changes With MAD Use". This study is evaluating two standard-of-care strategies used to prevent bite changes (occlusal changes) in patients treated with a Mandibular Advancement Device (MAD) for sleep-related breathing disorders such as obstructive sleep apnea (OSA). While MAD therapy is effective, it can lead to changes ...
What is the current status of trial NCT07103941?
This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2025-11-17. Estimated completion is 2026-04-30.
What conditions does trial NCT07103941 study?
This clinical trial studies the following conditions: Obstructive Sleep Apnea (OSA), Snoring, Sleep Related Breathing Disorder, Open Bite, Occlusal Changes.
What interventions are being tested in trial NCT07103941?
The interventions under investigation include: Exercise (BEHAVIORAL), AM Aligner (DEVICE).
Who is sponsoring clinical trial NCT07103941?
This trial is sponsored by Isabel Moreno Hay, which has 4 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07103941 being conducted?
This trial has 1 study location across Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obstructive Sleep Apnea (OSA)
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07103941's enrollment target sits among peer trials
30 9th of 12 higher than 4 of 12 other Obstructive Sleep Apnea (OSA) trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obstructive Sleep Apnea (OSA) trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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