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NCT07103941 · ClinicalTrials.gov registry record · NA
IOA Preventing Occlusal Changes With MAD Use
A NA study of Obstructive Sleep Apnea (OSA) and Snoring, sponsored by Isabel Moreno Hay.
- Recruiting
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT07103941 is a NA study of Obstructive Sleep Apnea (OSA) and Snoring that is actively recruiting participants, run by Isabel Moreno Hay. The registered enrollment target is 30 participants, below the 590-participant average among 12 other Obstructive Sleep Apnea (OSA) trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07103941, a NA study of Obstructive Sleep Apnea (OSA) and Snoring, is actively recruiting participants, sponsored by Isabel Moreno Hay.
- RECRUITING
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is evaluating two standard-of-care strategies used to prevent bite changes (occlusal changes) in patients treated with a Mandibular Advancement Device (MAD) for sleep-related breathing disorders such as obstructive sleep apnea (OSA). While MAD therapy is effective, it can lead to changes in how the teeth fit together, including the development of a posterior open bite. Participants in this study will be randomly assigned to one of two standard-of-care approaches: using an interocclusal aligner each morning after removing the MAD, or performing daily jaw exercises. Both methods aim to reduce the risk of occlusal changes. The study will follow participants over a 3-month period and includes dental evaluations, 3D oral scans, and short daily surveys. Findings from this research may help guide best practices for preserving occlusion during MAD therapy.
Conditions Studied
Interventions
- BEHAVIORAL Exercise
- DEVICE AM Aligner
Study Locations (1)
Kentucky
- Orofacial Pain Center - University of Kentucky - Kentucky Clinic - Lexington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2025-11-17 |
| Est. Completion | 2026-04-30 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07103941
The ClinicalTrials.gov registry entry for NCT07103941 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 590-participant average among 12 other Obstructive Sleep Apnea (OSA) trials with a reported enrollment target (95% lower). The listed sponsor is Isabel Moreno Hay, which has 4 total studies on file at ClinicalTrials.gov.
The record links to 7 conditions, with Obstructive Sleep Apnea (OSA) appearing as the primary indexed condition, and to 2 interventions - of which Exercise is the first listed.
NCT07103941 reports 1 study location spanning 1 distinct geographic area - top geographies include Kentucky.
Frequently Asked Questions
What is clinical trial NCT07103941 about?
NCT07103941 is a clinical study titled "IOA Preventing Occlusal Changes With MAD Use". This study is evaluating two standard-of-care strategies used to prevent bite changes (occlusal changes) in patients treated with a Mandibular Advancement Device (MAD) for sleep-related breathing disorders such as obstructive sleep apnea (OSA). While MAD therapy is effective, it can lead to changes ...
What is the current status of trial NCT07103941?
This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2025-11-17. Estimated completion is 2026-04-30.
What conditions does trial NCT07103941 study?
This clinical trial studies the following conditions: Obstructive Sleep Apnea (OSA), Snoring, Sleep Related Breathing Disorder, Open Bite, Occlusal Changes.
What interventions are being tested in trial NCT07103941?
The interventions under investigation include: Exercise (BEHAVIORAL), AM Aligner (DEVICE).
Who is sponsoring clinical trial NCT07103941?
This trial is sponsored by Isabel Moreno Hay, which has 4 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07103941 being conducted?
This trial has 1 study location across Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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