Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07103616 · ClinicalTrials.gov registry record · Phase 4
Individual Cerebral Hemodynamic Oxygenation Relationships - ICHOR 4
A Phase 4 study, sponsored by Children's Hospital Los Angeles.
- Not yet
- Registry status
- Phase 4
- Development phase
- 130
- Enrollment target
NCT07103616: Clinical Trial Phase 4 study, sponsored by Children's Hospital Los Angeles.
NCT07103616 is a Phase 4 study that has not yet begun recruiting, run by Children's Hospital Los Angeles. The registered enrollment target is 130 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (75% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07103616, a Phase 4 study, has not yet begun recruiting, sponsored by Children's Hospital Los Angeles.
- NOT YET RECRUITING
- Registry status
- Phase 4
- Development phase
- 130 participants
- Enrollment target
Study Summary
The goal of this clinical trial is to understand whether there are differences in the cerebral blood flow, and oxygen metabolism affected by two types of anesthesia: Propofol or Dexmedetomidine. Subjects who require clinical anesthesia for a clinical MRI and for whom the use of Propofol and Dexmedetomidine are in clinical equipoise will be offered to have the anesthesia they will receive during their MRI randomized. * Change in cerebral blood flow (ml blood/100g/min) * Change in cerebral metabolic rate of oxygen (ml O2/100g/min) Researchers will compare Propofol (Group A) to Dexmedetomidine (Group B) to see if compare the hemodynamic response to anesthesia. Participants will be randomized to receive one of two equally safe anesthetics (Propofol or Dexmedetomidine).
Primary Outcome
Phase contrast (PC) acquisition via MRI will be used to assess any impact of anesthesia on cerebral blood flow.
Interventions
- DRUG Randomization of Propofol or Dexmedetomidine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 130 participants |
| Start Date | 2025-09-01 |
| Est. Completion | 2028-09-01 |
| Phase | Phase 4 |
What is known before NCT07103616 opens enrollment
NCT07103616 is an interventional study that assigns participants to a tested intervention. The registered 130 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (75% lower).
The record links to 0 conditions, and to 1 intervention - of which Randomization of Propofol or Dexmedetomidine is the first listed.
NCT07103616 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07103616 about?
NCT07103616 is a clinical study titled "Individual Cerebral Hemodynamic Oxygenation Relationships - ICHOR 4". The goal of this clinical trial is to understand whether there are differences in the cerebral blood flow, and oxygen metabolism affected by two types of anesthesia: Propofol or Dexmedetomidine. Subjects who require clinical anesthesia for a clinical MRI and for whom the use of Propofol and Dexmedet...
What is the current status of trial NCT07103616?
This trial is currently not yet recruiting. It is a Phase 4 study. The enrollment target is 130 participants. The study started on 2025-09-01. Estimated completion is 2028-09-01.
What interventions are being tested in trial NCT07103616?
The interventions under investigation include: Randomization of Propofol or Dexmedetomidine (DRUG).
Who is sponsoring clinical trial NCT07103616?
This trial is sponsored by Children's Hospital Los Angeles, which has 119 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07103616's enrollment target sits among peer trials
130 622nd of 2000 higher than 1,370 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01492036 · 130 participants
Long-Term Follow-Up of Recipient of Gene Transfer Research
- NCT01631617 · 130 participants · Phase 2
Effects of Treatments on Atopic Dermatitis
- NCT02368041 · 130 participants
Utility of Thenar Near Infrared Spectroscopy (NIRS) in Pediatric Patients With Heart Failure
- NCT02604277 · 130 participants · NA
Suicidal Behavior in Patients Diagnosed With Bipolar Disorder
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI