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NCT07089121 · ClinicalTrials.gov registry record · Phase 1

Descartes-08 for Children, Adolescents, and Young Adults With Autoimmune Disorders

A Phase 1 study of Juvenile Dermatomyositis and ANCA-Associated Vasculitis (AAV), sponsored by Cartesian Therapeutics.

Recruiting
Registry status
Phase 1
Development phase
50
Enrollment target
1
Study location

NCT07089121 is a Phase 1 study of Juvenile Dermatomyositis and ANCA-Associated Vasculitis (AAV) that is actively recruiting participants, run by Cartesian Therapeutics. The registered enrollment target is 50 participants, below the 1,885-participant average among 3 other Juvenile Dermatomyositis trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07089121, a Phase 1 study of Juvenile Dermatomyositis and ANCA-Associated Vasculitis (AAV), is actively recruiting participants, sponsored by Cartesian Therapeutics.

RECRUITING
Registry status
Phase 1
Development phase
50 participants
Enrollment target
1
Study location

Study Summary

Safety, tolerability and efficacy of Descarte-08 in children, adolescents and young adults with childhood-onset systemic lupus erythematosus, ANCA-associated vasculitis, juvenile myasthenia gravis, and juvenile dermatomyositis

Interventions

  • DRUG Descartes-08

Study Locations (1)

Missouri

  • H03 - St Louis

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2026-01
Est. Completion 2026-12
Phase Phase 1

Sponsor

Cartesian Therapeutics

12 total trials

What the Registry Record Tells You About NCT07089121

The ClinicalTrials.gov registry entry for NCT07089121 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,885-participant average among 3 other Juvenile Dermatomyositis trials with a reported enrollment target (97% lower). The listed sponsor is Cartesian Therapeutics, which has 12 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Juvenile Dermatomyositis appearing as the primary indexed condition, and to 1 intervention - of which Descartes-08 is the first listed.

NCT07089121 reports 1 study location spanning 1 distinct geographic area - top geographies include Missouri.

Frequently Asked Questions

What is clinical trial NCT07089121 about?

NCT07089121 is a clinical study titled "Descartes-08 for Children, Adolescents, and Young Adults With Autoimmune Disorders". Safety, tolerability and efficacy of Descarte-08 in children, adolescents and young adults with childhood-onset systemic lupus erythematosus, ANCA-associated vasculitis, juvenile myasthenia gravis, and juvenile dermatomyositis

What is the current status of trial NCT07089121?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 50 participants. The study started on 2026-01. Estimated completion is 2026-12.

What conditions does trial NCT07089121 study?

This clinical trial studies the following conditions: Juvenile Dermatomyositis, ANCA-Associated Vasculitis (AAV), Childhood-onset Systemic Lupus Erythematous, Juvenile Myasthenia Gravis.

What interventions are being tested in trial NCT07089121?

The interventions under investigation include: Descartes-08 (DRUG).

Who is sponsoring clinical trial NCT07089121?

This trial is sponsored by Cartesian Therapeutics, which has 12 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07089121 being conducted?

This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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