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NCT07088120 · ClinicalTrials.gov registry record · NA
PRECISION-CPR: PRecision-Controlled Ventilation in CPR
A NA study, sponsored by Rush University Medical Center.
- Not yet
- Registry status
- NA
- Development phase
- 852
- Enrollment target
NCT07088120: Clinical Trial NA study, sponsored by Rush University Medical Center.
NCT07088120 is a NA study that has not yet begun recruiting, run by Rush University Medical Center. The registered enrollment target is 852 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (39% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07088120, a NA study, has not yet begun recruiting, sponsored by Rush University Medical Center.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 852 participants
- Enrollment target
Study Summary
Cardiac arrest is a life-threatening emergency that requires immediate treatment with cardiopulmonary resuscitation (CPR). While chest compressions circulate blood, manual ventilation provides oxygen to the patient. Current CPR guidelines recommend specific ventilation rates and tidal volumes, but studies show that clinicians often deliver too much or too little ventilation due to a lack of monitoring tools, potentially reducing the effectiveness of CPR and impacting survival. The PRECISION-CPR study is a multi-center, randomized controlled trial designed to evaluate whether using real-time feedback devices to precisely control ventilation during CPR can improve patient outcomes. Adult patients experiencing in-hospital cardiac arrest will be randomized to receive either standard manual ventilation guided by clinician experience or precision-controlled ventilation tailored to the patient's predicted body weight using real-time monitoring devices. The primary outcome of the study will be return of spontaneous circulation (ROSC). Secondary outcomes will include survival to hospital discharge, neurological recovery, and other clinical measures. By addressing the limitations of current ventilation practices, this study aims to generate evidence to guide future resuscitation guidelines and improve survival rates after cardiac arrest.
Primary Outcome
Documented presence of a palpable pulse and measurable blood pressure during resuscitation after initiation of CPR.
Interventions
- DEVICE Precision-Controlled Ventilation with Real-Time Feedback
- OTHER Standard Manual Ventilation During CPR
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 852 participants |
| Start Date | 2026-09-01 |
| Est. Completion | 2030-12-31 |
| Phase | NA |
What is known before NCT07088120 opens enrollment
NCT07088120 is an interventional study that assigns participants to a tested intervention. The registered 852 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (39% lower).
The record links to 0 conditions, and to 2 interventions - of which Precision-Controlled Ventilation with Real-Time Feedback is the first listed.
NCT07088120 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07088120 about?
NCT07088120 is a clinical study titled "PRECISION-CPR: PRecision-Controlled Ventilation in CPR". Cardiac arrest is a life-threatening emergency that requires immediate treatment with cardiopulmonary resuscitation (CPR). While chest compressions circulate blood, manual ventilation provides oxygen to the patient. Current CPR guidelines recommend specific ventilation rates and tidal volumes, but s...
What is the current status of trial NCT07088120?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 852 participants. The study started on 2026-09-01. Estimated completion is 2030-12-31.
What interventions are being tested in trial NCT07088120?
The interventions under investigation include: Precision-Controlled Ventilation with Real-Time Feedback (DEVICE), Standard Manual Ventilation During CPR (OTHER).
Who is sponsoring clinical trial NCT07088120?
This trial is sponsored by Rush University Medical Center, which has 320 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07088120's enrollment target sits among peer trials
852 131st of 2000 higher than 1,870 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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