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NCT07082725 · ClinicalTrials.gov registry record · Phase 3
A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease (NPC)
A Phase 3 study of Niemann-Pick Type C Disease, sponsored by Azafaros A.G..
- Recruiting
- Registry status
- Phase 3
- Development phase
- 72
- Enrollment target
- 20
- Study locations
NCT07082725 is a Phase 3 study of Niemann-Pick Type C Disease that is actively recruiting participants, run by Azafaros A.G.. The registered enrollment target is 72 participants. The trial reports 20 study locations across 17 states.
The verdict
NCT07082725, a Phase 3 study of Niemann-Pick Type C Disease, is actively recruiting participants, sponsored by Azafaros A.G..
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 72 participants
- Enrollment target
- 20
- Study locations
Study Summary
An 18-month double-blind, randomized, placebo-controlled, multicenter, Phase 3 study to evaluate the safety and efficacy of oral nizubaglustat (AZ-3102) in late-infantile and juvenile forms of Niemann-Pick type C disease
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Nizubaglustat
Study Locations (20)
Victoria
- Royal Melbourne Hospital - Parkville
- Royal Children's Hospital Melbourne - PIN - Parkville
Other
- Hospital Pequeno Principe - Curitiba
- SphinCS GmbH - Höchheim
Alberta
- M.A.G.I.C. Clinic Ltd. Metabolics and Genetics in Calgary - Calgary
- University of Alberta Medical Genetics Clinic - Edmonton
California
- UCSF Children's Hospital and Research Center at Oakland - Oakland
Minnesota
- University of Minnesota Medical School - Minneapolis
Texas
- Children's Medical Center Dallas - Dallas
Virginia
- Lysosomal Rare Disorders Research and Treatment Center - Fairfax
Buenos Aires
- Hospital Universitario Austral - Ciudad Autónoma Buenos Aires
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 72 participants |
| Start Date | 2025-06-30 |
| Est. Completion | 2027-11-04 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07082725
The ClinicalTrials.gov registry entry for NCT07082725 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 72 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Azafaros A.G., which has 3 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Niemann-Pick Type C Disease appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT07082725 reports 20 study locations spanning 17 distinct geographic areas - top geographies include Victoria, Other, Alberta.
Frequently Asked Questions
What is clinical trial NCT07082725 about?
NCT07082725 is a clinical study titled "A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease (NPC)". An 18-month double-blind, randomized, placebo-controlled, multicenter, Phase 3 study to evaluate the safety and efficacy of oral nizubaglustat (AZ-3102) in late-infantile and juvenile forms of Niemann-Pick type C disease
What is the current status of trial NCT07082725?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 72 participants. The study started on 2025-06-30. Estimated completion is 2027-11-04.
What conditions does trial NCT07082725 study?
This clinical trial studies the following conditions: Niemann-Pick Type C Disease.
What interventions are being tested in trial NCT07082725?
The interventions under investigation include: Placebo (DRUG), Nizubaglustat (DRUG).
Who is sponsoring clinical trial NCT07082725?
This trial is sponsored by Azafaros A.G., which has 3 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07082725 being conducted?
This trial has 20 study locations across California, Minnesota, Texas, Virginia, Buenos Aires. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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