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NCT07053085 · ClinicalTrials.gov registry record · Phase 2
A Study of Surgery and Radiotherapy in People With Breast Cancer
A Phase 2 study of Metastatic Breast Cancer and HER2-positive Breast Cancer, sponsored by Memorial Sloan Kettering Cancer Center.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 162
- Enrollment target
- 7
- Study locations
NCT07053085 is a Phase 2 study of Metastatic Breast Cancer and HER2-positive Breast Cancer that is actively recruiting participants, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 162 participants, below the 204-participant average among 139 other Metastatic Breast Cancer trials with a reported enrollment target (21% lower). The trial reports 7 study locations across 2 states.
The verdict
NCT07053085, a Phase 2 study of Metastatic Breast Cancer and HER2-positive Breast Cancer, is actively recruiting participants, sponsored by Memorial Sloan Kettering Cancer Center.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 162 participants
- Enrollment target
- 7
- Study locations
Study Summary
The researchers are doing this study to see if the combination of surgery, locoregional radiation therapy, SBRT (stereotactic body radiation therapy), and the usual approach is more effective in treating oligometastatic HER2-positive breast cancer than the usual approach alone. The researchers will also study the side effects of the study treatment.
Conditions Studied
Interventions
- RADIATION Radiotherapy
- PROCEDURE Lumpectomy or mastectomy
- DRUG Trastuzumab, Pertuzumab, Paclitaxel, or a combination of these drugs
Study Locations (7)
New York
- Memorial Sloan Kettering Suffolk-Commack (Limited Protocol Activities ) - Commack
- Memorial Sloan Kettering Westchester (Limited Protocol Activities) - Harrison
- Memorial Sloan Kettering Cancer Center (All protocol activites) - New York
- Memorial Sloan Kettering Nassau (Limited protocol activities) - Rockville Centre
New Jersey
- Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities) - Basking Ridge
- Memorial Sloan Kettering Monmouth (Limited Protocol Activities) - Middletown
- Memorial Sloan Kettering Bergen (Limited Protocol Activities) - Montvale
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 162 participants |
| Start Date | 2025-09-17 |
| Est. Completion | 2029-09-17 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07053085
The ClinicalTrials.gov registry entry for NCT07053085 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 162 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 204-participant average among 139 other Metastatic Breast Cancer trials with a reported enrollment target (21% lower). The listed sponsor is Memorial Sloan Kettering Cancer Center, which has 1,884 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Metastatic Breast Cancer appearing as the primary indexed condition, and to 3 interventions - of which Radiotherapy is the first listed.
NCT07053085 reports 7 study locations spanning 2 distinct geographic areas - top geographies include New York, New Jersey.
Frequently Asked Questions
What is clinical trial NCT07053085 about?
NCT07053085 is a clinical study titled "A Study of Surgery and Radiotherapy in People With Breast Cancer". The researchers are doing this study to see if the combination of surgery, locoregional radiation therapy, SBRT (stereotactic body radiation therapy), and the usual approach is more effective in treating oligometastatic HER2-positive breast cancer than the usual approach alone. The researchers will ...
What is the current status of trial NCT07053085?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 162 participants. The study started on 2025-09-17. Estimated completion is 2029-09-17.
What conditions does trial NCT07053085 study?
This clinical trial studies the following conditions: Metastatic Breast Cancer, HER2-positive Breast Cancer.
What interventions are being tested in trial NCT07053085?
The interventions under investigation include: Radiotherapy (RADIATION), Lumpectomy or mastectomy (PROCEDURE), Trastuzumab, Pertuzumab, Paclitaxel, or a combination of these drugs (DRUG).
Who is sponsoring clinical trial NCT07053085?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07053085 being conducted?
This trial has 7 study locations across New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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