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NCT07030725 · ClinicalTrials.gov registry record · Early Phase 1
Menthol Stimulation of Brown Adipose Tissue in Humans: Aim 1
A Early Phase 1 study of Regulation of Energy Expenditure, sponsored by Indiana University.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 24
- Enrollment target
- 1
- Study location
NCT07030725: Recruiting Early Phase 1 study of Regulation of Energy Expenditure, sponsored by Indiana University.
NCT07030725 is a Early Phase 1 study of Regulation of Energy Expenditure that is actively recruiting participants, run by Indiana University. The registered enrollment target is 24 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (55% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07030725, a Early Phase 1 study of Regulation of Energy Expenditure, is actively recruiting participants, sponsored by Indiana University.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 24 participants
- Enrollment target
- 1
- Study location
Study Summary
Brown adipose tissue becomes activated during cold conditions to increase thermogenesis (i.e., energy expenditure). Topical menthol application increases resting energy expenditure but it is unclear whether brown adipose tissue activation contributes to this rise in the energy expenditure. The overall goal with this project is to determine whether topical menthol application stimulates brown adipose tissue.
Primary Outcome
kcal/min
Conditions Studied
Interventions
- DRUG Menthol Gel
- DRUG Sham
- BEHAVIORAL Time control
Study Locations (1)
Indiana
- Indiana University - Bloomington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2025-03-27 |
| Est. Completion | 2026-09 |
| Phase | Early Phase 1 |
What NCT07030725 shows while recruiting
NCT07030725 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (55% lower).
The record links to 1 condition, with Regulation of Energy Expenditure appearing as the primary indexed condition, and to 3 interventions - of which Menthol Gel is the first listed.
NCT07030725 reports a single indexed study location in Indiana.
Frequently Asked Questions
What is clinical trial NCT07030725 about?
NCT07030725 is a clinical study titled "Menthol Stimulation of Brown Adipose Tissue in Humans: Aim 1". Brown adipose tissue becomes activated during cold conditions to increase thermogenesis (i.e., energy expenditure). Topical menthol application increases resting energy expenditure but it is unclear whether brown adipose tissue activation contributes to this rise in the energy expenditure. The overa...
What is the current status of trial NCT07030725?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 24 participants. The study started on 2025-03-27. Estimated completion is 2026-09.
What conditions does trial NCT07030725 study?
This clinical trial studies the following conditions: Regulation of Energy Expenditure.
What interventions are being tested in trial NCT07030725?
The interventions under investigation include: Menthol Gel (DRUG), Sham (DRUG), Time control (BEHAVIORAL).
Who is sponsoring clinical trial NCT07030725?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07030725 being conducted?
This trial has 1 study location across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07030725's enrollment target sits among peer trials
24 1037th of 2000 higher than 914 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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