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NCT07022678 · ClinicalTrials.gov registry record · Phase 3
Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia
A Phase 3 study, sponsored by Children's Oncology Group.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 556
- Enrollment target
NCT07022678 is a Phase 3 study that is actively recruiting participants, run by Children's Oncology Group. The registered enrollment target is 556 participants.
The verdict
NCT07022678, a Phase 3 study, is actively recruiting participants, sponsored by Children's Oncology Group.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 556 participants
- Enrollment target
Study Summary
This phase III trial compares the effect of xylitol dental wipes to dental wipes without xylitol for the reduction of bloodstream infection in children with acute myeloid leukemia (AML). Xylitol is a naturally occurring sugar compound found in fruits and vegetables. Xylitol has been shown to limit the growth of bacteria in the mouth, and to reduce cavities, plaque on the teeth, and inflammation of the gums. Treatment for AML includes chemotherapy. Patients receiving chemotherapy for AML have a risk of developing bloodstream infections. Bloodstream infections can make patients very sick, can contribute to delays in treatment, and can even cause death. In AML patients, bacteria or fungus (yeast) can sometimes enter the bloodstream from the mouth. Using xylitol dental wipes may help to reduce bloodstream infections in children being treated for AML.
Interventions
- PROCEDURE Biospecimen Collection
- OTHER Best Practice
- OTHER Electronic Health Record Review
- DRUG Cytarabine
- DRUG Placebo Administration
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 556 participants |
| Start Date | 2026-05-26 |
| Est. Completion | 2033-01-15 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07022678
The ClinicalTrials.gov registry entry for NCT07022678 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 556 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Children's Oncology Group, which has 342 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 5 interventions - of which Biospecimen Collection is the first listed.
NCT07022678 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07022678 about?
NCT07022678 is a clinical study titled "Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia". This phase III trial compares the effect of xylitol dental wipes to dental wipes without xylitol for the reduction of bloodstream infection in children with acute myeloid leukemia (AML). Xylitol is a naturally occurring sugar compound found in fruits and vegetables. Xylitol has been shown to limit t...
What is the current status of trial NCT07022678?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 556 participants. The study started on 2026-05-26. Estimated completion is 2033-01-15.
What interventions are being tested in trial NCT07022678?
The interventions under investigation include: Biospecimen Collection (PROCEDURE), Best Practice (OTHER), Electronic Health Record Review (OTHER), Cytarabine (DRUG), Placebo Administration (DRUG).
Who is sponsoring clinical trial NCT07022678?
This trial is sponsored by Children's Oncology Group, which has 342 total clinical trials registered on ClinicalTrials.gov.
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