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A Study to Learn About the Study Medicine Called Zavegepant (PF-07930207) in Children With a History of Migraine
NCT06995729 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of the study is to learn about safety and how the body processes the study medicine called Zavegepant (PF-07930207) in children with a history of migraine. This study helps understand how the medicine is changed and removed from the body after taking it. This study is seeking participants who: * Are children aged between 6 and less than 12 years old * Have had migraine for at least 6 months. * Weigh more than 15 kilograms All participants in this study will receive zavegepant as a nasal spray once (one spray into one nostril). The dose of the study medicine that each participant receives will depend on how much the participant weighs. The study will look at the experiences of the participants receiving the study medicine and collect data to better understand the possible benefits and unwanted effects of different doses of the study medicine. Participants will take part in this study for up to 10 weeks. During this time, they will have 3 study visits at the study clinic, and 2 follow-up phone calls.
Conditions Studied
Interventions
- DRUG Zavegepant
Study Locations (13)
North Carolina
- Accellacare - Piedmont — Statesville
- Accellacare of Piedmont HealthCare — Statesville
- Accellacare US Inc. — Winston-Salem
Utah
- Wasatch Clinical Research, LLC — Salt Lake City
- Granger Medical Holladay - Holladay Clinic — Salt Lake City
Arkansas
- Arkansas Children's Hospital — Little Rock
District of Columbia
- Velocity Clinical Research, Washington DC — Washington D.C.
Georgia
- Coastal Heritage Clinical Research — Hinesville
Minnesota
- Clinical Research Institute — Minneapolis
Nebraska
- Children's Hospital & Medical Center — Omaha
New York
- True North Neurology — Port Jefferson Station
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2025-05-16 |
| Est. Completion | 2027-08-12 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06995729
The ClinicalTrials.gov registry entry for NCT06995729 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Pfizer, which has 769 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Acute Treatment of Migraine appearing as the primary indexed condition, and to 1 intervention — of which Zavegepant is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06995729 reports 13 study locations spanning 10 distinct geographic areas — top geographies include North Carolina, Utah, Arkansas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06995729 about?
NCT06995729 is a clinical study titled "A Study to Learn About the Study Medicine Called Zavegepant (PF-07930207) in Children With a History of Migraine". The purpose of the study is to learn about safety and how the body processes the study medicine called Zavegepant (PF-07930207) in children with a history of migraine. This study helps understand how the medicine is changed and removed from the body after taking it. This study is seeking participan...
What is the current status of trial NCT06995729?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2025-05-16. Estimated completion is 2027-08-12.
What conditions does trial NCT06995729 study?
This clinical trial studies the following conditions: Acute Treatment of Migraine. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06995729?
The interventions under investigation include: Zavegepant (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06995729?
This trial is sponsored by Pfizer, which has 769 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06995729 being conducted?
This trial has 13 study locations across Arkansas, District of Columbia, Georgia, Minnesota, Nebraska. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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