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NCT06993155 · ClinicalTrials.gov registry record · Phase 2
A Clinical Trial Evaluating the Efficacy and Safety of Leflutrozole on Testicular Function
A Phase 2 study of Semen Quality, sponsored by ReproNovo Aps.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 200
- Enrollment target
- 4
- Study locations
NCT06993155 is a Phase 2 study of Semen Quality that is actively recruiting participants, run by ReproNovo Aps. The registered enrollment target is 200 participants. The trial reports 4 study locations across 3 states.
The verdict
NCT06993155, a Phase 2 study of Semen Quality, is actively recruiting participants, sponsored by ReproNovo Aps.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 200 participants
- Enrollment target
- 4
- Study locations
Study Summary
The goal of this clinical trial is to evaluate three doses of the drug leflutrozole on improvement of semen quality in men. It will also study the safety of leflutrozole. The main questions it aims to answer are: * Does leflutrozole improve semen quality? * What medical problems do participants experience when taking leflutrozole? Researchers will compare leflutrozole to a placebo (a look-alike substance that contains no drug). Participants will: * Take leflutrozole or a placebo orally once a week for 16 weeks. * Visit the clinic every 4 weeks for checkups and tests. * Provide semen samples to measure changes in semen quality. * Have their blood tested to measure hormone levels and ensure safety. * Be monitored for any side effects.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Leflutrozole, Dose 1
- DRUG Leflutrozole, Dose 2
- DRUG Leflutrozole, Dose 3
Study Locations (4)
California
- ReproNovo Investigational Site - North Hollywood
- ReproNovo Investigational Site - Pomona
New York
- ReproNovo Investigational Site - Garden City
Ohio
- ReproNovo Investigational Site - Middleburg Heights
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2025-06-27 |
| Est. Completion | 2026-11 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06993155
The ClinicalTrials.gov registry entry for NCT06993155 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is ReproNovo Aps, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Semen Quality appearing as the primary indexed condition, and to 4 interventions - of which Placebo is the first listed.
NCT06993155 reports 4 study locations spanning 3 distinct geographic areas - top geographies include California, New York, Ohio.
Frequently Asked Questions
What is clinical trial NCT06993155 about?
NCT06993155 is a clinical study titled "A Clinical Trial Evaluating the Efficacy and Safety of Leflutrozole on Testicular Function". The goal of this clinical trial is to evaluate three doses of the drug leflutrozole on improvement of semen quality in men. It will also study the safety of leflutrozole. The main questions it aims to answer are: * Does leflutrozole improve semen quality? * What medical problems do participants ex...
What is the current status of trial NCT06993155?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 200 participants. The study started on 2025-06-27. Estimated completion is 2026-11.
What conditions does trial NCT06993155 study?
This clinical trial studies the following conditions: Semen Quality.
What interventions are being tested in trial NCT06993155?
The interventions under investigation include: Placebo (DRUG), Leflutrozole, Dose 1 (DRUG), Leflutrozole, Dose 2 (DRUG), Leflutrozole, Dose 3 (DRUG).
Who is sponsoring clinical trial NCT06993155?
This trial is sponsored by ReproNovo Aps, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06993155 being conducted?
This trial has 4 study locations across California, New York, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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