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NCT06989749 · ClinicalTrials.gov registry record · NA
Transcranial Direct Current Stimulation and Modulation of Affect and Pain
A NA study of We Are Not Studying a Disease or Condition, sponsored by Trustees of Dartmouth College.
- Recruiting
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT06989749: Recruiting NA study of We Are Not Studying a Disease or Condition, sponsored by Trustees of Dartmouth College.
NCT06989749 is a NA study of We Are Not Studying a Disease or Condition that is actively recruiting participants, run by Trustees of Dartmouth College. The registered enrollment target is 50 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06989749, a NA study of We Are Not Studying a Disease or Condition, is actively recruiting participants, sponsored by Trustees of Dartmouth College.
- RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
This double-blind randomized crossover study aims to examine the effects of left primary motor cortex (M1) tDCS on evoked thermal pain perception, pain-related decision making, and placebo effects by manipulated pain and monetary offers accepted by others. The investigators plan to collect data for up to 50 participants who undergo four separate sessions: an initial pain calibration session and three experimental sessions with either anodal, cathodal, or sham tDCS. Each session includes pain testing before and after a single tDCS protocol (either anodal, cathodal, or sham), a pain-monetary decision-making task, and social placebo pain tests. All tasks following tDCS will take place inside the MR scanner. The investigators hypothesize that anodal M1 tDCS will decrease pain ratings, and that cathodal tDCS will increase them, both relative to the sham condition. The investigators will also examine the effects of M1 tDCS on social decision-making to examine whether it affects participants' valuation of pain and their altruistic behavior, as well as how these same factors impact pain sensation in the placebo task. The investigators hypothesize that participants will behave hyperaltruistically during the decision-making task, and that the same factors that influence choice will also impact pain perception in the same context.
Primary Outcome
Self-reported pain level following each thermal stimulus, measured on a visual analog scale. 0-100 scale with 0 indicating no pain and higher values indicating more pain.
Conditions Studied
Interventions
- OTHER Anodal tDCS
- OTHER Cathodal tDCS
- OTHER Sham tDCS
Study Locations (1)
New Hampshire
- Dartmouth College - Hanover
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2023-09-09 |
| Est. Completion | 2026-09 |
| Phase | NA |
What NCT06989749 shows while recruiting
NCT06989749 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 1 condition, with We Are Not Studying a Disease or Condition appearing as the primary indexed condition, and to 3 interventions - of which Anodal tDCS is the first listed.
NCT06989749 reports a single indexed study location in New Hampshire.
Frequently Asked Questions
What is clinical trial NCT06989749 about?
NCT06989749 is a clinical study titled "Transcranial Direct Current Stimulation and Modulation of Affect and Pain". This double-blind randomized crossover study aims to examine the effects of left primary motor cortex (M1) tDCS on evoked thermal pain perception, pain-related decision making, and placebo effects by manipulated pain and monetary offers accepted by others. The investigators plan to collect data for ...
What is the current status of trial NCT06989749?
This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2023-09-09. Estimated completion is 2026-09.
What conditions does trial NCT06989749 study?
This clinical trial studies the following conditions: We Are Not Studying a Disease or Condition.
What interventions are being tested in trial NCT06989749?
The interventions under investigation include: Anodal tDCS (OTHER), Cathodal tDCS (OTHER), Sham tDCS (OTHER).
Who is sponsoring clinical trial NCT06989749?
This trial is sponsored by Trustees of Dartmouth College, which has 31 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06989749 being conducted?
This trial has 1 study location across New Hampshire. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06989749's enrollment target sits among peer trials
50 1279th of 2000 higher than 622 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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