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NCT06989749 · ClinicalTrials.gov registry record · NA

Transcranial Direct Current Stimulation and Modulation of Affect and Pain

A NA study of We Are Not Studying a Disease or Condition, sponsored by Trustees of Dartmouth College.

Recruiting
Registry status
NA
Development phase
50
Enrollment target
1
Study location

NCT06989749 is a NA study of We Are Not Studying a Disease or Condition that is actively recruiting participants, run by Trustees of Dartmouth College. The registered enrollment target is 50 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT06989749, a NA study of We Are Not Studying a Disease or Condition, is actively recruiting participants, sponsored by Trustees of Dartmouth College.

RECRUITING
Registry status
NA
Development phase
50 participants
Enrollment target
1
Study location

Study Summary

This double-blind randomized crossover study aims to examine the effects of left primary motor cortex (M1) tDCS on evoked thermal pain perception, pain-related decision making, and placebo effects by manipulated pain and monetary offers accepted by others. The investigators plan to collect data for up to 50 participants who undergo four separate sessions: an initial pain calibration session and three experimental sessions with either anodal, cathodal, or sham tDCS. Each session includes pain testing before and after a single tDCS protocol (either anodal, cathodal, or sham), a pain-monetary decision-making task, and social placebo pain tests. All tasks following tDCS will take place inside the MR scanner. The investigators hypothesize that anodal M1 tDCS will decrease pain ratings, and that cathodal tDCS will increase them, both relative to the sham condition. The investigators will also examine the effects of M1 tDCS on social decision-making to examine whether it affects participants' valuation of pain and their altruistic behavior, as well as how these same factors impact pain sensation in the placebo task. The investigators hypothesize that participants will behave hyperaltruistically during the decision-making task, and that the same factors that influence choice will also impact pain perception in the same context.

Interventions

  • OTHER Anodal tDCS
  • OTHER Cathodal tDCS
  • OTHER Sham tDCS

Study Locations (1)

New Hampshire

  • Dartmouth College - Hanover

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2023-09-09
Est. Completion 2026-09
Phase NA

Sponsor

Trustees of Dartmouth College

31 total trials

What the Registry Record Tells You About NCT06989749

The ClinicalTrials.gov registry entry for NCT06989749 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Trustees of Dartmouth College, which has 31 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with We Are Not Studying a Disease or Condition appearing as the primary indexed condition, and to 3 interventions - of which Anodal tDCS is the first listed.

NCT06989749 reports 1 study location spanning 1 distinct geographic area - top geographies include New Hampshire.

Frequently Asked Questions

What is clinical trial NCT06989749 about?

NCT06989749 is a clinical study titled "Transcranial Direct Current Stimulation and Modulation of Affect and Pain". This double-blind randomized crossover study aims to examine the effects of left primary motor cortex (M1) tDCS on evoked thermal pain perception, pain-related decision making, and placebo effects by manipulated pain and monetary offers accepted by others. The investigators plan to collect data for ...

What is the current status of trial NCT06989749?

This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2023-09-09. Estimated completion is 2026-09.

What conditions does trial NCT06989749 study?

This clinical trial studies the following conditions: We Are Not Studying a Disease or Condition.

What interventions are being tested in trial NCT06989749?

The interventions under investigation include: Anodal tDCS (OTHER), Cathodal tDCS (OTHER), Sham tDCS (OTHER).

Who is sponsoring clinical trial NCT06989749?

This trial is sponsored by Trustees of Dartmouth College, which has 31 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06989749 being conducted?

This trial has 1 study location across New Hampshire. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.