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NCT06985420 · ClinicalTrials.gov registry record
The Effect of the Menstrual Cycle on Immune Cell Activity and Recovery After Resistance Exercise
A clinical trial of Resistance Exercise and Healthy Women, sponsored by University of Central Florida.
- Recruiting
- Registry status
- 40
- Enrollment target
- 1
- Study location
NCT06985420: Recruiting study of Resistance Exercise and Healthy Women, sponsored by University of Central Florida.
NCT06985420 is a study of Resistance Exercise and Healthy Women that is actively recruiting participants, run by University of Central Florida. The registered enrollment target is 40 participants, above the 21-participant average among 4 other Resistance Exercise trials with a reported enrollment target (90% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06985420, a study of Resistance Exercise and Healthy Women, is actively recruiting participants, sponsored by University of Central Florida.
- RECRUITING
- Registry status
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this observational study is to learn how the menstrual cycle affects immune cell activation, recruitment, and recovery responses after resistance exercise in healthy, resistance-trained women aged 18-40. The main questions it aims to answer are: Does the menstrual cycle influence neutrophil recruitment and adhesion after resistance exercise? Does the menstrual cycle affect markers of muscle damage and functional recovery? Researchers will compare three menstrual phases (early follicular, late follicular, and mid-luteal) to see if immune responses and recovery outcomes differ across these phases. Participants will: Complete resistance exercise protocols across three different menstrual cycle phases. Provide blood samples to assess immune cell activation and muscle damage markers. Track sleep, mood, and recovery with questionnaires and wear an accelerometer.
Primary Outcome
Measure: Neutrophil cell index (impedance reflecting neutrophil migration) using Real-Time Cell Analysis (RTCA). Objective: To assess the differences in neutrophil recruitment and adhesion across menstrual cycle phases (early follicular, late follicular, and mid-luteal). Time Frame: Assessed at 2 time points (baseline and 4 hours post exercise) on 3 experimental trial days (1 per menstrual cycle; up to 4 cycles per participant, over approximately 16 weeks).
Conditions Studied
Interventions
- OTHER Resistance exercise
- OTHER Menstrual Cycle Phases
Study Locations (1)
Florida
- University of Central Florida - Orlando
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2024-08-16 |
| Est. Completion | 2025-05 |
What NCT06985420 shows while recruiting
NCT06985420 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 40 participants, a relatively small participant target, above the 21-participant average among 4 other Resistance Exercise trials with a reported enrollment target (90% higher).
The record links to 3 conditions, with Resistance Exercise appearing as the primary indexed condition, and to 2 interventions - of which Resistance exercise is the first listed.
NCT06985420 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT06985420 about?
NCT06985420 is a clinical study titled "The Effect of the Menstrual Cycle on Immune Cell Activity and Recovery After Resistance Exercise". The goal of this observational study is to learn how the menstrual cycle affects immune cell activation, recruitment, and recovery responses after resistance exercise in healthy, resistance-trained women aged 18-40. The main questions it aims to answer are: Does the menstrual cycle influence neutro...
What is the current status of trial NCT06985420?
This trial is currently recruiting. The enrollment target is 40 participants. The study started on 2024-08-16. Estimated completion is 2025-05.
What conditions does trial NCT06985420 study?
This clinical trial studies the following conditions: Resistance Exercise, Healthy Women, Menstruation.
What interventions are being tested in trial NCT06985420?
The interventions under investigation include: Resistance exercise (OTHER), Menstrual Cycle Phases (OTHER).
Who is sponsoring clinical trial NCT06985420?
This trial is sponsored by University of Central Florida, which has 91 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06985420 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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