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NCT06985394 · ClinicalTrials.gov registry record · NA
Vascular Function and Oxidative Stress in Emergency Medical Responders
A NA study of Cardiovascular Function in EMTs, sponsored by University of Delaware.
- Recruiting
- Registry status
- NA
- Development phase
- 45
- Enrollment target
- 1
- Study location
NCT06985394: Recruiting NA study of Cardiovascular Function in EMTs, sponsored by University of Delaware.
NCT06985394 is a NA study of Cardiovascular Function in EMTs that is actively recruiting participants, run by University of Delaware. The registered enrollment target is 45 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06985394, a NA study of Cardiovascular Function in EMTs, is actively recruiting participants, sponsored by University of Delaware.
- RECRUITING
- Registry status
- NA
- Development phase
- 45 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to characterize blood vessel function and oxidative stress (a harmful condition that damages cells and tissues) in emergency medical technicians (EMTs). The main questions it aims to answer are: 1. Does an overnight shift work in emergency medical technicians reduce blood vessel function and increase oxidative stress? 2. Can supplementing with antioxidants help reduce the negative effects of night shift work in emergency medical technicians? Researchers will compare antioxidants to a placebo (a look-alike substance that contains no drug) to see if antioxidants work in reducing the negative effects of night shift work in emergency medical technicians. Participants will: 1\. Report to the lab two separate times following an overnight shift to assess blood vessel functioning and oxidative stress 3. Take an antioxidant supplement or placebo during each night of shift work.
Primary Outcome
Flow-mediated dilation (FMD) is a frequently practiced non-invasive technique which images artery structure and blood flow before, during, and after a period of blood flow occlusion and subsequent increases in blood flow. This creates stress on the inner lining (i.e., endothelium) of the vasculature, inducing a cascade of events which results in relaxation of the smooth muscle surrounding the vessel. Reduced functioning of this mechanism is significantly associated with cardiovascular complicati
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Placebo
- DIETARY_SUPPLEMENT Antioxidant cocktail
Study Locations (1)
Delaware
- University of Delaware - Newark
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 45 participants |
| Start Date | 2025-05-14 |
| Est. Completion | 2025-10 |
| Phase | NA |
What NCT06985394 shows while recruiting
NCT06985394 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 45 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Cardiovascular Function in EMTs appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT06985394 reports a single indexed study location in Delaware.
Frequently Asked Questions
What is clinical trial NCT06985394 about?
NCT06985394 is a clinical study titled "Vascular Function and Oxidative Stress in Emergency Medical Responders". The goal of this clinical trial is to characterize blood vessel function and oxidative stress (a harmful condition that damages cells and tissues) in emergency medical technicians (EMTs). The main questions it aims to answer are: 1. Does an overnight shift work in emergency medical technicians redu...
What is the current status of trial NCT06985394?
This trial is currently recruiting. It is a NA study. The enrollment target is 45 participants. The study started on 2025-05-14. Estimated completion is 2025-10.
What conditions does trial NCT06985394 study?
This clinical trial studies the following conditions: Cardiovascular Function in EMTs.
What interventions are being tested in trial NCT06985394?
The interventions under investigation include: Placebo (DIETARY_SUPPLEMENT), Antioxidant cocktail (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT06985394?
This trial is sponsored by University of Delaware, which has 106 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06985394 being conducted?
This trial has 1 study location across Delaware. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06985394's enrollment target sits among peer trials
45 1411th of 2000 higher than 578 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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