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NCT06984744 · ClinicalTrials.gov registry record · NA
4-day Plaque Accumulation Model Evaluating Compound Containing Gum
A NA study of Dental Plaque Accumulation, sponsored by Lactea Therapeutics.
- Recruiting
- Registry status
- NA
- Development phase
- 32
- Enrollment target
- 1
- Study location
NCT06984744: Recruiting NA study of Dental Plaque Accumulation, sponsored by Lactea Therapeutics.
NCT06984744 is a NA study of Dental Plaque Accumulation that is actively recruiting participants, run by Lactea Therapeutics. The registered enrollment target is 32 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06984744, a NA study of Dental Plaque Accumulation, is actively recruiting participants, sponsored by Lactea Therapeutics.
- RECRUITING
- Registry status
- NA
- Development phase
- 32 participants
- Enrollment target
- 1
- Study location
Study Summary
This will be a single-blind, single-center, 3-way crossover, randomized controlled clinical trial with 3 treatment periods utilizing 32 subjects. (Fig 1, in protocol) Each treatment period will be 4 days (96 hours +/-3 hours) in accordance with the plaque accumulation model using one of the following treatment groups: an active compound MIIP-E2 gum (experimental regimen), an inactive compound gum (negative control regimen), and a no-gum (control regimen).
Primary Outcome
Dental plaque was identified using a disclosing solution and scored using the Turesky modification of the Quigley-Hein Plaque Index (PLI). The index score was scored between 0 and 5, with 0 = no plaque detected and 5= = Plaque covering 2/3 or more of the tooth's crown. The remaining values are based on the amount of plaque covering the tooth. The higher the score, the more plaque accumulated and the worse the outcome for the surface. Each tooth, except the third molars, will be scored at six sit
Conditions Studied
Interventions
- DEVICE MIIP-E2 containing gum
- DEVICE placebo gum without MIIP-E2
Study Locations (1)
Indiana
- Oral Health Research Institute - Indianapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2025-06-23 |
| Est. Completion | 2026-02-27 |
| Phase | NA |
What NCT06984744 shows while recruiting
NCT06984744 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Dental Plaque Accumulation appearing as the primary indexed condition, and to 2 interventions - of which MIIP-E2 containing gum is the first listed.
NCT06984744 reports a single indexed study location in Indiana.
Frequently Asked Questions
What is clinical trial NCT06984744 about?
NCT06984744 is a clinical study titled "4-day Plaque Accumulation Model Evaluating Compound Containing Gum". This will be a single-blind, single-center, 3-way crossover, randomized controlled clinical trial with 3 treatment periods utilizing 32 subjects. (Fig 1, in protocol) Each treatment period will be 4 days (96 hours +/-3 hours) in accordance with the plaque accumulation model using one of the followin...
What is the current status of trial NCT06984744?
This trial is currently recruiting. It is a NA study. The enrollment target is 32 participants. The study started on 2025-06-23. Estimated completion is 2026-02-27.
What conditions does trial NCT06984744 study?
This clinical trial studies the following conditions: Dental Plaque Accumulation.
What interventions are being tested in trial NCT06984744?
The interventions under investigation include: MIIP-E2 containing gum (DEVICE), placebo gum without MIIP-E2 (DEVICE).
Who is sponsoring clinical trial NCT06984744?
This trial is sponsored by Lactea Therapeutics, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06984744 being conducted?
This trial has 1 study location across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06984744's enrollment target sits among peer trials
32 1579th of 2000 higher than 409 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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