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NCT06976840 · ClinicalTrials.gov registry record · NA
Rapid Antidepressant Dynamics in Acute Neuromodulation Treatments
A NA study, sponsored by Marta Peciña, MD PhD.
- Recruiting
- Registry status
- NA
- Development phase
- 200
- Enrollment target
NCT06976840 is a NA study that is actively recruiting participants, run by Marta Peciña, MD PhD. The registered enrollment target is 200 participants.
The verdict
NCT06976840, a NA study, is actively recruiting participants, sponsored by Marta Peciña, MD PhD.
- RECRUITING
- Registry status
- NA
- Development phase
- 200 participants
- Enrollment target
Study Summary
The goal of this clinical trial is to learn how different types of non-invasive brain stimulation affect mood and brain function in adults with major depressive disorder (MDD). It will also study how brain stimulation may work together with antidepressant treatments. The main questions this study aims to answer are: How do different patterns of brain stimulation affect mood in people with depression? Do brain networks involved in emotion and self-reflection respond differently depending on the type of stimulation? What are the combined effects of brain stimulation and antidepressant treatments on mood and brain activity? Researchers will compare different brain stimulation patterns and target areas to understand their individual and combined effects. Participants will: Receive three types of brain stimulation (intermittent, continuous, and sham) in different sessions Undergo MRI scans during the administration of either a fast-acting or conventional antidepressant. Complete mood assessments during the scan and for one week after each session This study may help identify brain-based strategies to improve treatment for depression. In addition, a subset of participants (\~10) will complete a reward-guided decision-making fMRI task for feasibility purposes.
Interventions
- DEVICE Intermittent theta burst stimulation
- DEVICE Sham theta burst stimulation
- DEVICE Continuous theta burst stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2026-05-15 |
| Est. Completion | 2030-08-01 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06976840
The ClinicalTrials.gov registry entry for NCT06976840 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Marta Peciña, MD PhD, which has 4 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 3 interventions - of which Intermittent theta burst stimulation is the first listed.
NCT06976840 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT06976840 about?
NCT06976840 is a clinical study titled "Rapid Antidepressant Dynamics in Acute Neuromodulation Treatments". The goal of this clinical trial is to learn how different types of non-invasive brain stimulation affect mood and brain function in adults with major depressive disorder (MDD). It will also study how brain stimulation may work together with antidepressant treatments. The main questions this study a...
What is the current status of trial NCT06976840?
This trial is currently recruiting. It is a NA study. The enrollment target is 200 participants. The study started on 2026-05-15. Estimated completion is 2030-08-01.
What interventions are being tested in trial NCT06976840?
The interventions under investigation include: Intermittent theta burst stimulation (DEVICE), Sham theta burst stimulation (DEVICE), Continuous theta burst stimulation (DEVICE).
Who is sponsoring clinical trial NCT06976840?
This trial is sponsored by Marta Peciña, MD PhD, which has 4 total clinical trials registered on ClinicalTrials.gov.
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