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NCT06962774 · ClinicalTrials.gov registry record · Phase 1
An Investigational Study of ESK-001 in Participants With Normal Renal Function and Participants With Mild, Moderate, and Severe Impaired Renal Function
A Phase 1 study, sponsored by Alumis.
- Completed
- Registry status
- Phase 1
- Development phase
- 16
- Enrollment target
NCT06962774: Completed Phase 1 study, sponsored by Alumis.
NCT06962774 is a Phase 1 study that has completed, run by Alumis. The registered enrollment target is 16 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06962774, a Phase 1 study, has completed, sponsored by Alumis.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 16 participants
- Enrollment target
Study Summary
This a phase 1, open label, single dose, parallel cohort study to determine the pharmacokinetics (PK) of study drug (ESK-001) in healthy volunteer participants, and participants with mild, moderate, and severe renal impairment.
Interventions
- DRUG ESK-001
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2025-04-23 |
| Est. Completion | 2025-08-01 |
| Phase | Phase 1 |
What the finished NCT06962774 record still lists
NCT06962774 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower).
The record links to 0 conditions, and to 1 intervention - of which ESK-001 is the first listed.
NCT06962774 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06962774 about?
NCT06962774 is a clinical study titled "An Investigational Study of ESK-001 in Participants With Normal Renal Function and Participants With Mild, Moderate, and Severe Impaired Renal Function". This a phase 1, open label, single dose, parallel cohort study to determine the pharmacokinetics (PK) of study drug (ESK-001) in healthy volunteer participants, and participants with mild, moderate, and severe renal impairment.
What is the current status of trial NCT06962774?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2025-04-23. Estimated completion is 2025-08-01.
What interventions are being tested in trial NCT06962774?
The interventions under investigation include: ESK-001 (DRUG).
Who is sponsoring clinical trial NCT06962774?
This trial is sponsored by Alumis, which has 13 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06962774's enrollment target sits among peer trials
16 1786th of 2000 higher than 203 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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