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NCT06962657 · ClinicalTrials.gov registry record · Phase 2

Mitigating Toxic Impact: The Role of Coenzyme Q10 in Post-Exposure Protection

A Phase 2 study, sponsored by University of California, San Diego.

Not yet
Registry status
Phase 2
Development phase
20
Enrollment target

NCT06962657: Clinical Trial Phase 2 study, sponsored by University of California, San Diego.

NCT06962657 is a Phase 2 study that has not yet begun recruiting, run by University of California, San Diego. The registered enrollment target is 20 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (85% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06962657, a Phase 2 study, has not yet begun recruiting, sponsored by University of California, San Diego.

NOT YET RECRUITING
Registry status
Phase 2
Development phase
20 participants
Enrollment target

Study Summary

This research study is being conducted to see if coenzyme Q10 (a nutritional supplement) might help to prevent and/or alleviate symptoms and health consequences and help to improve quality of life and physical function in residents affected by the February 2023 East Palestine, Ohio train derailment. This is a pilot study that is not powered to achieve benefit but seek to examine effect size and variance to aid in power calculations for a potential future better powered study.

Primary Outcome

Number of symptoms (out of 20 on the UCSD Symptom Score Survey) showing more favorable change (trend or effect) on active treatment vs. on placebo. Outcomes are assessed as change from start of that treatment phase (from baseline for phase 1; and from 3 month crossover visit for phase 2).

Interventions

  • DRUG Placebo
  • DRUG Ubiquinone 100 mg Oral Soft Gel

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2026-05-15
Est. Completion 2028-10-01
Phase Phase 2
University of California, San Diego

775 total trials

What is known before NCT06962657 opens enrollment

NCT06962657 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (85% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT06962657 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT06962657 about?

NCT06962657 is a clinical study titled "Mitigating Toxic Impact: The Role of Coenzyme Q10 in Post-Exposure Protection". This research study is being conducted to see if coenzyme Q10 (a nutritional supplement) might help to prevent and/or alleviate symptoms and health consequences and help to improve quality of life and physical function in residents affected by the February 2023 East Palestine, Ohio train derailment....

What is the current status of trial NCT06962657?

This trial is currently not yet recruiting. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2026-05-15. Estimated completion is 2028-10-01.

What interventions are being tested in trial NCT06962657?

The interventions under investigation include: Placebo (DRUG), Ubiquinone 100 mg Oral Soft Gel (DRUG).

Who is sponsoring clinical trial NCT06962657?

This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT06962657's enrollment target sits among peer trials

20 1805th of 2000 higher than 107 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06962657, the US trial registry maintained by the National Library of Medicine. NCT06962657 (small enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.