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NCT06950060 · ClinicalTrials.gov registry record · NA

AMPLIFI: Adaptive Modulation of Plasticity Through Lactate and Fitness Interventions

A NA study, sponsored by University of Alabama at Birmingham.

Not yet
Registry status
NA
Development phase
48
Enrollment target

NCT06950060 is a NA study that has not yet begun recruiting, run by University of Alabama at Birmingham. The registered enrollment target is 48 participants.

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The verdict

NCT06950060, a NA study, has not yet begun recruiting, sponsored by University of Alabama at Birmingham.

NOT YET RECRUITING
Registry status
NA
Development phase
48 participants
Enrollment target

Study Summary

The AMPLIFI study (Adaptive Modulation of Plasticity through Lactate and Fitness Interventions) investigates how short-term aerobic exercise influences brain plasticity and learning in older adults and stroke survivors. The study compares three groups: one performing aerobic cycling at an intensity that elevates lactate levels, one performing low-intensity exercise, and one receiving health education without exercise. All participants will complete motor learning tasks and undergo brain-stimulation testing using transcranial magnetic stimulation (TMS) to assess how well the brain responds to training. The goal is to understand whether different types of exercise can improve brain function, movement, and memory, and how the body's response to exercise (like lactate levels) might support brain health. This research may help identify low-cost, non-invasive interventions-such as targeted exercise-that improve motor and cognitive outcomes in aging and stroke recovery.

Interventions

  • BEHAVIORAL Moderate Intensity Aerobic Exercise
  • BEHAVIORAL High intensity cycling
  • BEHAVIORAL Low-intensity cycling
  • BEHAVIORAL Health education session

Trial Details

FieldValue
Enrollment Target 48 participants
Start Date 2026-05-14
Est. Completion 2030-01-01
Phase NA

Sponsor

University of Alabama at Birmingham

1,160 total trials

What the Registry Record Tells You About NCT06950060

The ClinicalTrials.gov registry entry for NCT06950060 describes a study currently listed as not yet recruiting, categorized as NA. The registered enrollment target is 48 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Alabama at Birmingham, which has 1,160 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Moderate Intensity Aerobic Exercise is the first listed.

NCT06950060 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT06950060 about?

NCT06950060 is a clinical study titled "AMPLIFI: Adaptive Modulation of Plasticity Through Lactate and Fitness Interventions". The AMPLIFI study (Adaptive Modulation of Plasticity through Lactate and Fitness Interventions) investigates how short-term aerobic exercise influences brain plasticity and learning in older adults and stroke survivors. The study compares three groups: one performing aerobic cycling at an intensity ...

What is the current status of trial NCT06950060?

This trial is currently not yet recruiting. It is a NA study. The enrollment target is 48 participants. The study started on 2026-05-14. Estimated completion is 2030-01-01.

What interventions are being tested in trial NCT06950060?

The interventions under investigation include: Moderate Intensity Aerobic Exercise (BEHAVIORAL), High intensity cycling (BEHAVIORAL), Low-intensity cycling (BEHAVIORAL), Health education session (BEHAVIORAL).

Who is sponsoring clinical trial NCT06950060?

This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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