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NCT06949644 · ClinicalTrials.gov registry record · NA
Pupillometry in Delayed Sleep Wake Phase Disorder
A NA study, sponsored by Northwestern University.
- Recruiting
- Registry status
- NA
- Development phase
- 220
- Enrollment target
NCT06949644 is a NA study that is actively recruiting participants, run by Northwestern University. The registered enrollment target is 220 participants.
The verdict
NCT06949644, a NA study, is actively recruiting participants, sponsored by Northwestern University.
- RECRUITING
- Registry status
- NA
- Development phase
- 220 participants
- Enrollment target
Study Summary
The goal of this observational study is to characterize the pupil light response in patients with delayed sleep-wake phase disorder. A subset of participants will take part in a clinical trial to determine if increasing serotonin can alter the circadian response to light. The main questions it aims to answer is: Are there differences in the light response in patients with delayed sleep-wake phase disorder? Does citalopram increase melatonin suppression in patients with delayed sleep-wake phase disorder? Participants will complete activity and melatonin testing at home to determine their circadian timing. This will be followed by an eye test looking at the pupil response to different light stimuli. A subset of participants will complete two inpatient admissions where melatonin levels will be sampled and they will be exposed to a bright light. During one round of testing they will receive a placebo and in the other round of testing they will take a single dose of citalopram, a selective serotonin reuptake inhibitor.
Interventions
- COMBINATION_PRODUCT Light and Citalopram
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 220 participants |
| Start Date | 2025-09-01 |
| Est. Completion | 2029-08-31 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06949644
The ClinicalTrials.gov registry entry for NCT06949644 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 220 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Northwestern University, which has 1,209 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Light and Citalopram is the first listed.
NCT06949644 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT06949644 about?
NCT06949644 is a clinical study titled "Pupillometry in Delayed Sleep Wake Phase Disorder". The goal of this observational study is to characterize the pupil light response in patients with delayed sleep-wake phase disorder. A subset of participants will take part in a clinical trial to determine if increasing serotonin can alter the circadian response to light. The main questions it aims ...
What is the current status of trial NCT06949644?
This trial is currently recruiting. It is a NA study. The enrollment target is 220 participants. The study started on 2025-09-01. Estimated completion is 2029-08-31.
What interventions are being tested in trial NCT06949644?
The interventions under investigation include: Light and Citalopram (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT06949644?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
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