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NCT06929455 · ClinicalTrials.gov registry record · NA
Using Bitter Taste Receptor Blockers to Improve the Palatability of Pediatric Medicines
A NA study of Healthy Adults, sponsored by Monell Chemical Senses Center.
- Recruiting
- Registry status
- NA
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT06929455 is a NA study of Healthy Adults that is actively recruiting participants, run by Monell Chemical Senses Center. The registered enrollment target is 100 participants, above the 83-participant average among 33 other Healthy Adults trials with a reported enrollment target (20% higher). The trial reports 1 study location across 1 state.
The verdict
NCT06929455, a NA study of Healthy Adults, is actively recruiting participants, sponsored by Monell Chemical Senses Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
Many people, particularly small children, must take drugs in liquid form because they cannot swallow pills or capsules. The bad taste of some liquid drugs can keep patients from taking drugs they need for their health. Our main goal in this research study is find ingredients that might make drugs taste better. Participants in this research study will be healthy adults between the ages of 18 and 60 years old. Participants will taste samples (liquids or gels) containing active pharmaceutical ingredients (substances in medications that produce desired health effects). After tasting each sample participants will spit out the sample and rinse with water (no samples will be swallowed). Active pharmaceutical ingredients of current interest are: 1) tenofovir alafenamide, used to treat HIV infection and hepatitis B, 2) rifampicin, used to treat tuberculosis, 3) rifapentine, used to treat tuberculosis, and 4) levofloxacin, used to treat various bacterial infections). Other active pharmaceutical ingredients may be added as the study goes forward. Participants will be instructed to taste samples both with and without experimental flavor ingredients added and judge how the samples taste. People who volunteer for the study will be instructed to complete many repeated visits to the Monell Center (University City area of Philadelphia) for tasting sessions. Tasting visits will last between 1 and 2 hours.
Conditions Studied
Interventions
- OTHER Flavor additives
Study Locations (1)
Pennsylvania
- Monell Chemical Senses Center - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2025-03-18 |
| Est. Completion | 2026-11-01 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06929455
The ClinicalTrials.gov registry entry for NCT06929455 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 83-participant average among 33 other Healthy Adults trials with a reported enrollment target (20% higher). The listed sponsor is Monell Chemical Senses Center, which has 16 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Healthy Adults appearing as the primary indexed condition, and to 1 intervention - of which Flavor additives is the first listed.
NCT06929455 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT06929455 about?
NCT06929455 is a clinical study titled "Using Bitter Taste Receptor Blockers to Improve the Palatability of Pediatric Medicines". Many people, particularly small children, must take drugs in liquid form because they cannot swallow pills or capsules. The bad taste of some liquid drugs can keep patients from taking drugs they need for their health. Our main goal in this research study is find ingredients that might make drugs ta...
What is the current status of trial NCT06929455?
This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2025-03-18. Estimated completion is 2026-11-01.
What conditions does trial NCT06929455 study?
This clinical trial studies the following conditions: Healthy Adults.
What interventions are being tested in trial NCT06929455?
The interventions under investigation include: Flavor additives (OTHER).
Who is sponsoring clinical trial NCT06929455?
This trial is sponsored by Monell Chemical Senses Center, which has 16 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06929455 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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