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NCT06925295 · ClinicalTrials.gov registry record · Phase 2
Using Xe MRI to Guide Radiation Therapy for Lung Cancer
A Phase 2 study of Imaging Techniques, sponsored by Sean Fain.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 15
- Enrollment target
- 1
- Study location
NCT06925295: Recruiting Phase 2 study of Imaging Techniques, sponsored by Sean Fain.
NCT06925295 is a Phase 2 study of Imaging Techniques that is actively recruiting participants, run by Sean Fain. The registered enrollment target is 15 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06925295, a Phase 2 study of Imaging Techniques, is actively recruiting participants, sponsored by Sean Fain.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 15 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this research study is to explore using MRI scans with xenon to better image lung function, how lung function changes after radiation therapy, and to guide radiation therapy away from parts of the lung that have good function. This project is foundational to performing additional studies to establish if novel MRI imaging can serve as a guidance tool for lung cancer radiation treatment.
Primary Outcome
is the incidence of PFT evidence of radiation pneumonitis and lung function change. Change in spirometry will be reported as the mean±SD of these measurements for each treatment study visit, and the mean difference of these measurements from baseline.
Conditions Studied
Interventions
- OTHER Quality of Life Questionnaire
- DRUG Xenon MRI
- DIAGNOSTIC_TEST Pulmonary Function Testing
- OTHER Medical Research Council Dyspnea score
- OTHER St. George's Respiratory Questionnaire
Study Locations (1)
Iowa
- University of Iowa - Iowa City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2025-08-30 |
| Est. Completion | 2027-01 |
| Phase | Phase 2 |
What NCT06925295 shows while recruiting
NCT06925295 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (89% lower).
The record links to 1 condition, with Imaging Techniques appearing as the primary indexed condition, and to 5 interventions - of which Quality of Life Questionnaire is the first listed.
NCT06925295 reports a single indexed study location in Iowa.
Frequently Asked Questions
What is clinical trial NCT06925295 about?
NCT06925295 is a clinical study titled "Using Xe MRI to Guide Radiation Therapy for Lung Cancer". The purpose of this research study is to explore using MRI scans with xenon to better image lung function, how lung function changes after radiation therapy, and to guide radiation therapy away from parts of the lung that have good function. This project is foundational to performing additional stud...
What is the current status of trial NCT06925295?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 15 participants. The study started on 2025-08-30. Estimated completion is 2027-01.
What conditions does trial NCT06925295 study?
This clinical trial studies the following conditions: Imaging Techniques.
What interventions are being tested in trial NCT06925295?
The interventions under investigation include: Quality of Life Questionnaire (OTHER), Xenon MRI (DRUG), Pulmonary Function Testing (DIAGNOSTIC_TEST), Medical Research Council Dyspnea score (OTHER), St. George's Respiratory Questionnaire (OTHER).
Who is sponsoring clinical trial NCT06925295?
This trial is sponsored by Sean Fain, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06925295 being conducted?
This trial has 1 study location across Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06925295's enrollment target sits among peer trials
15 1920th of 2000 higher than 60 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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