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RECRUITING NA

Transcranial Direct Current Stimulation for Post Treatment Lyme Disease

NCT06915324 · View on ClinicalTrials.gov ↗

Study Summary

The primary purpose of this pilot study is to investigate a novel approach to the treatment of cognitive symptoms that persist despite prior antibiotic treatment for Lyme disease (Post treatment Lyme Disease or PTLD). Aim 1: The primary aim of this study is to assess whether the processing speed of individuals with PTLD can be enhanced by combining transcranial direct current stimulation (tDCS) with computer based cognitive training games. To achieve this aim, over a 4-week period, all individuals with PTLD will participate in at home adaptive cognitive training combined with either active stimulation or sham stimulation. Aim 2: To determine if treatment benefit in processing speed is sustained, the study will compare the sham and active groups 8 weeks after completion of study treatment.

Interventions

  • DEVICE Transcranial Direct Current Stimulation (tDCS)
  • BEHAVIORAL Cognitive training

Study Locations (2)

California

  • University of California, San Francisco — San Francisco

New York

  • Columbia University Department of Psychiatry — New York

Trial Details

FieldValue
Enrollment Target 110 participants
Start Date 2025-07-14
Est. Completion 2027-08
Phase NA

Sponsor

Columbia University

875 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06915324

The ClinicalTrials.gov registry entry for NCT06915324 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 110 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Columbia University, which has 875 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Post-Treatment Lyme Disease appearing as the primary indexed condition, and to 2 interventions — of which Transcranial Direct Current Stimulation (tDCS) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06915324 reports 2 study locations spanning 2 distinct geographic areas — top geographies include California, New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06915324 about?

NCT06915324 is a clinical study titled "Transcranial Direct Current Stimulation for Post Treatment Lyme Disease". The primary purpose of this pilot study is to investigate a novel approach to the treatment of cognitive symptoms that persist despite prior antibiotic treatment for Lyme disease (Post treatment Lyme Disease or PTLD). Aim 1: The primary aim of this study is to assess whether the processing speed of...

What is the current status of trial NCT06915324?

This trial is currently recruiting. It is a NA study. The enrollment target is 110 participants. The study started on 2025-07-14. Estimated completion is 2027-08.

What conditions does trial NCT06915324 study?

This clinical trial studies the following conditions: Post-Treatment Lyme Disease. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06915324?

The interventions under investigation include: Transcranial Direct Current Stimulation (tDCS) (DEVICE), Cognitive training (BEHAVIORAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06915324?

This trial is sponsored by Columbia University, which has 875 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06915324 being conducted?

This trial has 2 study locations across California, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial