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NCT06910241 · ClinicalTrials.gov registry record · Phase 3
Lidocaine Versus Diphenhydramine to Achieve Local Anesthesia for Laceration Repairs
A Phase 3 study of Laceration of Skin, sponsored by Florida Atlantic University.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT06910241 is a Phase 3 study of Laceration of Skin that is actively recruiting participants, run by Florida Atlantic University. The registered enrollment target is 100 participants. The trial reports 1 study location across 1 state.
The verdict
NCT06910241, a Phase 3 study of Laceration of Skin, is actively recruiting participants, sponsored by Florida Atlantic University.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
Diphenhydramine, when injected locally, has been shown to achieve a certain level of local anesthesia. It has been documented for use in simple bedside procedures, however there is a gap in knowledge in its comparison to lidocaine. The purpose of the study is to determine if local infiltration of diphenhydramine is noninferior to the use of lidocaine 1% when trying to achieve local anesthesia for simple laceration repair. Patients who present to the emergency department with a simple laceration will be enrolled in the study. Patients will be evaluated for the pain of the injection as well as the pain of the laceration repair procedure post injection.
Conditions Studied
Interventions
- DRUG Lidocaine
- DRUG Diphenhydramine
Study Locations (1)
Florida
- Bethesda Hospital East - Boynton Beach
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2025-09-03 |
| Est. Completion | 2028-06-30 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06910241
The ClinicalTrials.gov registry entry for NCT06910241 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Florida Atlantic University, which has 27 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Laceration of Skin appearing as the primary indexed condition, and to 2 interventions - of which Lidocaine is the first listed.
NCT06910241 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.
Frequently Asked Questions
What is clinical trial NCT06910241 about?
NCT06910241 is a clinical study titled "Lidocaine Versus Diphenhydramine to Achieve Local Anesthesia for Laceration Repairs". Diphenhydramine, when injected locally, has been shown to achieve a certain level of local anesthesia. It has been documented for use in simple bedside procedures, however there is a gap in knowledge in its comparison to lidocaine. The purpose of the study is to determine if local infiltration of di...
What is the current status of trial NCT06910241?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 100 participants. The study started on 2025-09-03. Estimated completion is 2028-06-30.
What conditions does trial NCT06910241 study?
This clinical trial studies the following conditions: Laceration of Skin.
What interventions are being tested in trial NCT06910241?
The interventions under investigation include: Lidocaine (DRUG), Diphenhydramine (DRUG).
Who is sponsoring clinical trial NCT06910241?
This trial is sponsored by Florida Atlantic University, which has 27 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06910241 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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