Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT06907225 · ClinicalTrials.gov registry record

Physiological Responses to Heat Stress During High-risk Events

A clinical trial, sponsored by United States Army Research Institute of Environmental Medicine.

Recruiting
Registry status
150
Enrollment target

NCT06907225: Recruiting study, sponsored by United States Army Research Institute of Environmental Medicine.

NCT06907225 is a clinical trial that is actively recruiting participants, run by United States Army Research Institute of Environmental Medicine. The registered enrollment target is 150 participants. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT06907225 is actively recruiting participants, sponsored by United States Army Research Institute of Environmental Medicine.

RECRUITING
Registry status
150 participants
Enrollment target

Study Summary

Exertional heat stroke (EHS) affects \~500 Military Personnel and over 100 Soldiers every year, and it is believed that these numbers are underreported. EHS is the most severe form of exertional heat illness (EHI) and can result in substantial, long-lasting organ damage, and even death in severe cases. Based on current knowledge and training needs, it is impossible to prevent every EHS - which shifts the focus from exclusively prevention to a combination of prevention, treatment, and enhancing recovery as much as possible. While many risk factors have been identified and there are adequate treatments available, biomarkers associated with heat stroke risk, recovery, and return-to-duty (RTD) remain largely unclear. The purpose of the proposed study is to enhance knowledge surrounding biomarkers of EHS and long-term health consequences that result from EHS. The investigators will recruit research volunteers for a field study in order to collect pre-, post-, and follow-up measures from a high-risk EHS event (i.e. ruck marches, timed runs) this will allow us to have a basis for comparison between Soldiers who collapse with EHS (from previously collected data) and those that complete high-risk events, but do not collapse. This will allow for comparison between the groups to identify EHS-specific biomarkers that could aid in recovery and RTD decisions for Soldiers.

Primary Outcome

Body temperature recorded during training

Interventions

  • OTHER None-placebo

Trial Details

FieldValue
Enrollment Target 150 participants
Start Date 2025-05-31
Est. Completion 2026-09

What NCT06907225 shows while recruiting

NCT06907225 is an observational study that tracks outcomes without assigning an intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap.

The record links to 0 conditions, and to 1 intervention - of which None-placebo is the first listed.

NCT06907225 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT06907225 about?

NCT06907225 is a clinical study titled "Physiological Responses to Heat Stress During High-risk Events". Exertional heat stroke (EHS) affects \~500 Military Personnel and over 100 Soldiers every year, and it is believed that these numbers are underreported. EHS is the most severe form of exertional heat illness (EHI) and can result in substantial, long-lasting organ damage, and even death in severe cas...

What is the current status of trial NCT06907225?

This trial is currently recruiting. The enrollment target is 150 participants. The study started on 2025-05-31. Estimated completion is 2026-09.

What interventions are being tested in trial NCT06907225?

The interventions under investigation include: None-placebo (OTHER).

Who is sponsoring clinical trial NCT06907225?

This trial is sponsored by United States Army Research Institute of Environmental Medicine, which has 59 total clinical trials registered on ClinicalTrials.gov.

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00412594 · 150 participants · Phase 2

    Cladribine and Rituximab in Treating Patients With Hairy Cell Leukemia

  • NCT01484730 · 150 participants

    A Pilot Study to Evaluate Multi-Spectral and Laser Speckle Imaging and Multiphoton Microscopy During Vascular Occlusion

  • NCT01985919 · 150 participants

    Protocol for Facilitating the Acquisition of Research Bone Marrow and Blood Samples

  • NCT02016248 · 150 participants · NA

    SBRT Boost for Unfavorable Prostate Cancer'

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT06907225, the US trial registry maintained by the National Library of Medicine. NCT06907225 (mid enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.