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NCT06902272 · ClinicalTrials.gov registry record · Phase 2

ctDNA to Predict Response to Chemo-Immunotherapy and Detect Minimal Residual Disease in Non-Small Cell Lung Cancer

A Phase 2 study of Non-Small Cell Lung Cancer, sponsored by University of Miami.

Recruiting
Registry status
Phase 2
Development phase
30
Enrollment target
1
Study location

NCT06902272 is a Phase 2 study of Non-Small Cell Lung Cancer that is actively recruiting participants, run by University of Miami. The registered enrollment target is 30 participants, below the 659-participant average among 449 other Non-Small Cell Lung Cancer trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06902272, a Phase 2 study of Non-Small Cell Lung Cancer, is actively recruiting participants, sponsored by University of Miami.

RECRUITING
Registry status
Phase 2
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to determine if a blood test called circulating tumor DNA (ctDNA) can be used to predict how well patients will respond to treatment and if there is any cancer left after surgery. The investigators will also study if a drug called pembrolizumab can help prevent the cancer from coming back in patients who are ctDNA-positive or who have evidence of cancer after treatment and surgery.

Conditions Studied

Interventions

  • DRUG Pembrolizumab
  • DIAGNOSTIC_TEST Circulating Tumor Deoxyribonucleic acid (ctDNA) Assay
  • DRUG Platinum Doublet Chemotherapy

Study Locations (1)

Florida

  • University of Miami - Miami

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2025-06-11
Est. Completion 2029-06-11
Phase Phase 2

Sponsor

University of Miami

721 total trials

What the Registry Record Tells You About NCT06902272

The ClinicalTrials.gov registry entry for NCT06902272 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 659-participant average among 449 other Non-Small Cell Lung Cancer trials with a reported enrollment target (95% lower). The listed sponsor is University of Miami, which has 721 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Non-Small Cell Lung Cancer appearing as the primary indexed condition, and to 3 interventions - of which Pembrolizumab is the first listed.

NCT06902272 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.

Frequently Asked Questions

What is clinical trial NCT06902272 about?

NCT06902272 is a clinical study titled "ctDNA to Predict Response to Chemo-Immunotherapy and Detect Minimal Residual Disease in Non-Small Cell Lung Cancer". The purpose of this study is to determine if a blood test called circulating tumor DNA (ctDNA) can be used to predict how well patients will respond to treatment and if there is any cancer left after surgery. The investigators will also study if a drug called pembrolizumab can help prevent the cance...

What is the current status of trial NCT06902272?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 2025-06-11. Estimated completion is 2029-06-11.

What conditions does trial NCT06902272 study?

This clinical trial studies the following conditions: Non-Small Cell Lung Cancer.

What interventions are being tested in trial NCT06902272?

The interventions under investigation include: Pembrolizumab (DRUG), Circulating Tumor Deoxyribonucleic acid (ctDNA) Assay (DIAGNOSTIC_TEST), Platinum Doublet Chemotherapy (DRUG).

Who is sponsoring clinical trial NCT06902272?

This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06902272 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.