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NCT06895746 · ClinicalTrials.gov registry record
Multi-omics Study in Citrin Deficiency
A clinical trial of Citrin Deficiency, sponsored by Johannes Haeberle.
- Active
- Registry status
- 100
- Enrollment target
- 20
- Study locations
NCT06895746 is a study of Citrin Deficiency that is active but no longer recruiting, run by Johannes Haeberle. The registered enrollment target is 100 participants. The trial reports 20 study locations across 12 states.
The verdict
NCT06895746, a study of Citrin Deficiency, is active but no longer recruiting, sponsored by Johannes Haeberle.
- ACTIVE NOT RECRUITING
- Registry status
- 100 participants
- Enrollment target
- 20
- Study locations
Study Summary
Citrin deficiency (CD) is an underdiagnosed and understudied condition characterized by several distinct phenotypes: 1) neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD), 2) the adaptation or silent period, 3) "failure to thrive and dyslipidemia" form of CD (FTTDCD), and 4) citrullinemia type II (CTLN2), with the latter representing the final and most severe form of the condition. There is currently no cure for CD and patients manage their symptoms with lifelong dietary intervention and regular checkups with their physicians. A major hurdle in developing effective treatments for CD is the lack of effective biomarkers that track well with disease severity or measure the effectiveness of therapeutics. The present study aims to identify robust circulating biomarkers of CD through analysis of blood samples from CD patients.
Conditions Studied
Study Locations (20)
Other
- Chiba Children's Hospital - Chiba
- Kumamoto University Hospital - Kumamoto
- Yamagata University School of Medicine - Yamagata
- Taiwan University Hospital - Taipei
- Taipei Veterans General Hospital - Taipei
- University Hospitals Birmingham NHS Foundation Trust - Birmingham
- Birmingham Women's and Children's Hospital NHF Foundation Trust - Birmingham
- Bristol Royal Hospital for Children - Bristol
- University College London Hospital - London
New York
- Mount Sinai Hospital - New York
Fukuoka
- Kurume University - Kurume-shi
Iruma
- Saitama Medical University - Saitama
Kanagawa
- Saiseikai Yokohama City Eastern Hospital - Yokohama
Minato City
- Jikei University Hospital - Tokyo
Miyagi
- Tohoku University - Sendai
Nagano
- Shinshu University Hospital - Matsumoto
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2023-04-01 |
| Est. Completion | 2026-12 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06895746
The ClinicalTrials.gov registry entry for NCT06895746 describes a study currently listed as active not recruiting, categorized as an unspecified phase. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Johannes Haeberle, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Citrin Deficiency appearing as the primary indexed condition, and to 0 interventions.
NCT06895746 reports 20 study locations spanning 12 distinct geographic areas - top geographies include Other, New York, Fukuoka.
Frequently Asked Questions
What is clinical trial NCT06895746 about?
NCT06895746 is a clinical study titled "Multi-omics Study in Citrin Deficiency". Citrin deficiency (CD) is an underdiagnosed and understudied condition characterized by several distinct phenotypes: 1) neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD), 2) the adaptation or silent period, 3) "failure to thrive and dyslipidemia" form of CD (FTTDCD), and 4) citru...
What is the current status of trial NCT06895746?
This trial is currently active not recruiting. The enrollment target is 100 participants. The study started on 2023-04-01. Estimated completion is 2026-12.
What conditions does trial NCT06895746 study?
This clinical trial studies the following conditions: Citrin Deficiency.
Who is sponsoring clinical trial NCT06895746?
This trial is sponsored by Johannes Haeberle, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06895746 being conducted?
This trial has 20 study locations across New York, Fukuoka, Iruma, Kanagawa, Minato City. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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