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NCT06893081 · ClinicalTrials.gov registry record · Phase 1
A Study of Carbamazepine (CBZ) and MK-8527 in Healthy Adult Participants (MK-8527-012)
A Phase 1 study, sponsored by Merck Sharp & Dohme.
- Completed
- Registry status
- Phase 1
- Development phase
- 16
- Enrollment target
NCT06893081: Completed Phase 1 study, sponsored by Merck Sharp & Dohme.
NCT06893081 is a Phase 1 study that has completed, run by Merck Sharp & Dohme. The registered enrollment target is 16 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06893081, a Phase 1 study, has completed, sponsored by Merck Sharp & Dohme.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 16 participants
- Enrollment target
Study Summary
The goal of this study is to learn what happens to MK-8527 in a healthy person's body over time when MK-8527 is given alone and with the medication CBZ.
Primary Outcome
Blood samples will be collected to determine the AUC0-inf of MK-8527 in plasma
Interventions
- DRUG MK-8527
- DRUG CBZ
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2025-04-28 |
| Est. Completion | 2025-07-17 |
| Phase | Phase 1 |
What the finished NCT06893081 record still lists
NCT06893081 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower).
The record links to 0 conditions, and to 2 interventions - of which MK-8527 is the first listed.
NCT06893081 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06893081 about?
NCT06893081 is a clinical study titled "A Study of Carbamazepine (CBZ) and MK-8527 in Healthy Adult Participants (MK-8527-012)". The goal of this study is to learn what happens to MK-8527 in a healthy person's body over time when MK-8527 is given alone and with the medication CBZ.
What is the current status of trial NCT06893081?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2025-04-28. Estimated completion is 2025-07-17.
What interventions are being tested in trial NCT06893081?
The interventions under investigation include: MK-8527 (DRUG), CBZ (DRUG).
Who is sponsoring clinical trial NCT06893081?
This trial is sponsored by Merck Sharp & Dohme, which has 558 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06893081's enrollment target sits among peer trials
16 1786th of 2000 higher than 203 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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