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NCT06882772 · ClinicalTrials.gov registry record · Phase 1
Butyric Acid Supplementation for Gut Improvement After Cardiac Surgery in Kids
A Phase 1 study, sponsored by University of Nebraska.
- Not yet
- Registry status
- Phase 1
- Development phase
- 105
- Enrollment target
NCT06882772 is a Phase 1 study that has not yet begun recruiting, run by University of Nebraska. The registered enrollment target is 105 participants.
The verdict
NCT06882772, a Phase 1 study, has not yet begun recruiting, sponsored by University of Nebraska.
- NOT YET RECRUITING
- Registry status
- Phase 1
- Development phase
- 105 participants
- Enrollment target
Study Summary
Butyric acid has been shown to promote gut health and improve the microbiome in multiple adult studies. In preliminary studies in older children with inflammatory bowel disease, butyric acid was shown to be safe. However, it's suitability for infants and young children with congenital heart disease (CHD) has yet to be determined. This study will examine butyric acid supplementation in infants and children, ages 1 month to 3 years, with CHD who require cardiac surgery with cardiopulmonary bypass. Study goals include determining the safety and tolerability of butyric acid supplementation before cardiac surgery, and to identify changes in gut microbial communities, metabolic profile, and genetic markers intestinal function. Also, the study seeks to establish a reduction in inflammation (inflammatory signaling) after cardiopulmonary bypass (CPB) in participants receiving butyric acid.
Interventions
- DRUG Placebo
- DRUG 2 mL SunButyrate-TG
- DRUG 4 mL SunButyrate-TG
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 105 participants |
| Start Date | 2026-03 |
| Est. Completion | 2029-12 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06882772
The ClinicalTrials.gov registry entry for NCT06882772 describes a study currently listed as not yet recruiting, categorized as Phase 1. The registered enrollment target is 105 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Nebraska, which has 407 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT06882772 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT06882772 about?
NCT06882772 is a clinical study titled "Butyric Acid Supplementation for Gut Improvement After Cardiac Surgery in Kids". Butyric acid has been shown to promote gut health and improve the microbiome in multiple adult studies. In preliminary studies in older children with inflammatory bowel disease, butyric acid was shown to be safe. However, it's suitability for infants and young children with congenital heart disease ...
What is the current status of trial NCT06882772?
This trial is currently not yet recruiting. It is a Phase 1 study. The enrollment target is 105 participants. The study started on 2026-03. Estimated completion is 2029-12.
What interventions are being tested in trial NCT06882772?
The interventions under investigation include: Placebo (DRUG), 2 mL SunButyrate-TG (DRUG), 4 mL SunButyrate-TG (DRUG).
Who is sponsoring clinical trial NCT06882772?
This trial is sponsored by University of Nebraska, which has 407 total clinical trials registered on ClinicalTrials.gov.
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