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NCT06874244 · ClinicalTrials.gov registry record · Early Phase 1

Clinical Evaluation of no Needle Dental Anesthesia Compared to Syringe Anesthesia Delivery

A Early Phase 1 study, sponsored by Louisiana State University Health Sciences Center in New Orleans.

Completed
Registry status
Early Phase 1
Development phase
20
Enrollment target

NCT06874244: Completed Early Phase 1 study, sponsored by Louisiana State University Health Sciences Center in New Orleans.

NCT06874244 is a Early Phase 1 study that has completed, run by Louisiana State University Health Sciences Center in New Orleans. The registered enrollment target is 20 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (62% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06874244, a Early Phase 1 study, has completed, sponsored by Louisiana State University Health Sciences Center in New Orleans.

COMPLETED
Registry status
Early Phase 1
Development phase
20 participants
Enrollment target

Study Summary

The purpose of the study is to evaluate two different ways to administer the numbing solution. One is with a conventional needle and syringe the other method iontophoresis is a machine that supplies a weak current through electrodes that touch your teeth. Both methods use an anesthesia solution to make your teeth numb but the iontophoresis system contains no needle and the delivery device does not penetrate the gum.

Primary Outcome

Pain response in the gingiva will be recorded as a yes/no after a painful stimulus is applied using a probe on the buccal and palatal soft tissues.

Interventions

  • DRUG Local Anesthesia (lidocaine hydrochloride)
  • DRUG Iontophoresis of Tetracaine and oxymetazoline

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2024-08-01
Est. Completion 2025-07-01
Phase Early Phase 1

What the finished NCT06874244 record still lists

NCT06874244 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (62% lower).

The record links to 0 conditions, and to 2 interventions - of which Local Anesthesia (lidocaine hydrochloride) is the first listed.

NCT06874244 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT06874244 about?

NCT06874244 is a clinical study titled "Clinical Evaluation of no Needle Dental Anesthesia Compared to Syringe Anesthesia Delivery". The purpose of the study is to evaluate two different ways to administer the numbing solution. One is with a conventional needle and syringe the other method iontophoresis is a machine that supplies a weak current through electrodes that touch your teeth. Both methods use an anesthesia solution to m...

What is the current status of trial NCT06874244?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 20 participants. The study started on 2024-08-01. Estimated completion is 2025-07-01.

What interventions are being tested in trial NCT06874244?

The interventions under investigation include: Local Anesthesia (lidocaine hydrochloride) (DRUG), Iontophoresis of Tetracaine and oxymetazoline (DRUG).

Who is sponsoring clinical trial NCT06874244?

This trial is sponsored by Louisiana State University Health Sciences Center in New Orleans, which has 45 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT06874244's enrollment target sits among peer trials

20 1157th of 2000 higher than 710 of 2,000 other Early Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06874244, the US trial registry maintained by the National Library of Medicine. NCT06874244 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.