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NCT06856668 · ClinicalTrials.gov registry record · NA
A Megastudy of Single-Session Interventions for Depression
A NA study, sponsored by Northwestern University.
- Completed
- Registry status
- NA
- Development phase
- 7,505
- Enrollment target
NCT06856668: Completed NA study, sponsored by Northwestern University.
NCT06856668 is a NA study that has completed, run by Northwestern University. The registered enrollment target is 7,505 participants, above the 1,403-participant average among 58,714 other NA trials with a reported enrollment target (435% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06856668, a NA study, has completed, sponsored by Northwestern University.
- COMPLETED
- Registry status
- NA
- Development phase
- 7,505 participants
- Enrollment target
Study Summary
This project aims to learn if new kinds of digital single-session interventions (SSIs) for depression could be effective for American adults. Many existing SSIs are delivered in a simple text-based format. However, it might be that different kinds of SSIs (in terms of both content and style) also have potential for scalable impact. Specifically, this study will investigate the effectiveness of 11 innovative SSIs by comparing them to a passive control and to an existing SSI with established efficacy.
Primary Outcome
The Patient Health Questionnaire-9 is a validated and self-administered measure to assess depression symptom severity in the general population. Participants are asked to rate how often they are bothered by 9 items (e.g., Poor appetite or overeating) on a scale of 0 (Not at all) to 3 (Nearly every day). Total score can range from 0 to 27, with higher scores indicating higher symptom severity.
Interventions
- BEHAVIORAL Behavioral Activation (Action Brings Change Project 10-Minute Version)
- BEHAVIORAL Mindful Acceptance
- BEHAVIORAL Moral Elevation
- BEHAVIORAL Mindful Attention Skills
- BEHAVIORAL 5 Habits to Beat Depression
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7,505 participants |
| Start Date | 2025-03-11 |
| Est. Completion | 2025-06-24 |
| Phase | NA |
What the finished NCT06856668 record still lists
NCT06856668 is an interventional study that assigns participants to a tested intervention. Its 7,505 participants enrollment target places it among the larger protocols in the corpus, above the 1,403-participant average among 58,714 other NA trials with a reported enrollment target (435% higher).
The record links to 0 conditions, and to 5 interventions - of which Behavioral Activation (Action Brings Change Project 10-Minute Version) is the first listed.
NCT06856668 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06856668 about?
NCT06856668 is a clinical study titled "A Megastudy of Single-Session Interventions for Depression". This project aims to learn if new kinds of digital single-session interventions (SSIs) for depression could be effective for American adults. Many existing SSIs are delivered in a simple text-based format. However, it might be that different kinds of SSIs (in terms of both content and style) also ha...
What is the current status of trial NCT06856668?
This trial is currently completed. It is a NA study. The enrollment target is 7,505 participants. The study started on 2025-03-11. Estimated completion is 2025-06-24.
What interventions are being tested in trial NCT06856668?
The interventions under investigation include: Behavioral Activation (Action Brings Change Project 10-Minute Version) (BEHAVIORAL), Mindful Acceptance (BEHAVIORAL), Moral Elevation (BEHAVIORAL), Mindful Attention Skills (BEHAVIORAL), 5 Habits to Beat Depression (BEHAVIORAL).
Who is sponsoring clinical trial NCT06856668?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06856668's enrollment target sits among peer trials
7,505 20th of 2000 higher than 1,981 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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