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NCT06853184 · ClinicalTrials.gov registry record · Phase 2

Study Evaluating the Efficacy and Safety of Artesunate

A Phase 2 study, sponsored by Amivas.

Recruiting
Registry status
Phase 2
Development phase
90
Enrollment target

NCT06853184: Recruiting Phase 2 study, sponsored by Amivas.

NCT06853184 is a Phase 2 study that is actively recruiting participants, run by Amivas. The registered enrollment target is 90 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (32% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06853184, a Phase 2 study, is actively recruiting participants, sponsored by Amivas.

RECRUITING
Registry status
Phase 2
Development phase
90 participants
Enrollment target

Study Summary

This study is a randomized, open-label, active comparator-controlled, dose-ranging trial of the efficacy and safety of IV artesunate in combination with IV GCV or oral VGCV and SOC treatment compared to GCV or VGCV monotherapy and SOC treatment in SOT recipients with clinically significant CMV infection.

Primary Outcome

Determine if Artesunate for Injection (intravenous \[IV\] artesunate) when administered in combination with IV Ganciclovir (GCV) and/or oral valganciclovir (VGCV) and standard of care (SOC) treatment impacts change of cytomegalovirus (CMV) DNAemia compared with those who only received GCV or VGCV and SOC treatment

Interventions

  • DRUG Artesunate
  • DRUG Ganciclovir (GCV)

Trial Details

FieldValue
Enrollment Target 90 participants
Start Date 2025-08-01
Est. Completion 2028-06-30
Phase Phase 2
Amivas

2 total trials

What NCT06853184 shows while recruiting

NCT06853184 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 90 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (32% lower).

The record links to 0 conditions, and to 2 interventions - of which Artesunate is the first listed.

NCT06853184 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT06853184 about?

NCT06853184 is a clinical study titled "Study Evaluating the Efficacy and Safety of Artesunate". This study is a randomized, open-label, active comparator-controlled, dose-ranging trial of the efficacy and safety of IV artesunate in combination with IV GCV or oral VGCV and SOC treatment compared to GCV or VGCV monotherapy and SOC treatment in SOT recipients with clinically significant CMV infec...

What is the current status of trial NCT06853184?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 90 participants. The study started on 2025-08-01. Estimated completion is 2028-06-30.

What interventions are being tested in trial NCT06853184?

The interventions under investigation include: Artesunate (DRUG), Ganciclovir (GCV) (DRUG).

Who is sponsoring clinical trial NCT06853184?

This trial is sponsored by Amivas, which has 2 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT06853184's enrollment target sits among peer trials

90 772nd of 2000 higher than 1,199 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06853184, the US trial registry maintained by the National Library of Medicine. NCT06853184 (small enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.