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NCT06845813 · ClinicalTrials.gov registry record · Phase 1
Study to Investigate the Effect of Renal Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD6234
A Phase 1 study, sponsored by AstraZeneca.
- Completed
- Registry status
- Phase 1
- Development phase
- 24
- Enrollment target
NCT06845813: Completed Phase 1 study, sponsored by AstraZeneca.
NCT06845813 is a Phase 1 study that has completed, run by AstraZeneca. The registered enrollment target is 24 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06845813, a Phase 1 study, has completed, sponsored by AstraZeneca.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 24 participants
- Enrollment target
Study Summary
This study will evaluate the pharmacokinetics (PK), safety, and tolerability of single subcutaneous dose of AZD6234 with end stage renal disease, severe, and possibly moderate and mild renal impairment in comparison to a matched healthy control group.
Primary Outcome
Area under plasma concentration-time curve from time zero to the last measurable concentration
Interventions
- DRUG AZD6234
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2025-02-24 |
| Est. Completion | 2025-09-30 |
| Phase | Phase 1 |
What the finished NCT06845813 record still lists
NCT06845813 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower).
The record links to 0 conditions, and to 1 intervention - of which AZD6234 is the first listed.
NCT06845813 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06845813 about?
NCT06845813 is a clinical study titled "Study to Investigate the Effect of Renal Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD6234". This study will evaluate the pharmacokinetics (PK), safety, and tolerability of single subcutaneous dose of AZD6234 with end stage renal disease, severe, and possibly moderate and mild renal impairment in comparison to a matched healthy control group.
What is the current status of trial NCT06845813?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2025-02-24. Estimated completion is 2025-09-30.
What interventions are being tested in trial NCT06845813?
The interventions under investigation include: AZD6234 (DRUG).
Who is sponsoring clinical trial NCT06845813?
This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06845813's enrollment target sits among peer trials
24 1520th of 2000 higher than 405 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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