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NCT06842225 · ClinicalTrials.gov registry record · NA
Interactive Roles of Cardiorespiratory Fitness and Adiposity on Glucose and Vascular Control After Physical Inactivity
A NA study, sponsored by Miami University.
- Not yet
- Registry status
- NA
- Development phase
- 48
- Enrollment target
NCT06842225 is a NA study that has not yet begun recruiting, run by Miami University. The registered enrollment target is 48 participants.
The verdict
NCT06842225, a NA study, has not yet begun recruiting, sponsored by Miami University.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 48 participants
- Enrollment target
Study Summary
The far-reaching negative health effects of the reduced physical activity (RPA) epidemic are often overlooked by the general population and health professionals. Short-term RPA induces cardiometabolic dysfunction, including impaired glucose control and vascular function, that may precede disease development. The impact of existing health status on RPA-induced cardiometabolic dysfunction and recovery of impaired glucose control following RPA is unexplored. Thus, the investigators' objectives are 1) to investigate the effect of existing health status (cardiorespiratory fitness and adiposity) on the recovery of impaired glucose control following a period of RPA and 2) to determine the role of vascular function as a mechanism of impaired glucose control. The investigators' final objective is to 3) expose undergraduate students to meritorious biomedical clinical research methods. The investigators have piloted the clinical research methods and analysis with undergraduate researcher associates and are well-prepared to complete this proposal. Preliminary data show that low cardiorespiratory fitness and/or high adiposity impair the recovery of glucose control following short-term RPA. Thus, the investigators aim to examine the interactive role of health status (cardiorespiratory fitness and adiposity) on the ability to recover impaired glucose control following short-term RPA. The investigators also seek to examine changes in vascular function as a mechanism of recovery of impaired glucose control following a return to normal PA. The investigators will recruit men and women with divergent health status (cardiorespiratory fitness and adiposity) to examine glucose control and vascular function during 7-d of normal PA, 7-d of RPA, and 7-d of resumption of normal RA. Continuous glucose monitoring and oral glucose tolerance tests will be performed to assess glucose control. Increases in vascular shear stress induced by passive leg movement and central arterial stiffness will be
Interventions
- OTHER reduced physical activity
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2025-06-01 |
| Est. Completion | 2029-06-30 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06842225
The ClinicalTrials.gov registry entry for NCT06842225 describes a study currently listed as not yet recruiting, categorized as NA. The registered enrollment target is 48 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Miami University, which has 6 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which reduced physical activity is the first listed.
NCT06842225 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT06842225 about?
NCT06842225 is a clinical study titled "Interactive Roles of Cardiorespiratory Fitness and Adiposity on Glucose and Vascular Control After Physical Inactivity". The far-reaching negative health effects of the reduced physical activity (RPA) epidemic are often overlooked by the general population and health professionals. Short-term RPA induces cardiometabolic dysfunction, including impaired glucose control and vascular function, that may precede disease dev...
What is the current status of trial NCT06842225?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 48 participants. The study started on 2025-06-01. Estimated completion is 2029-06-30.
What interventions are being tested in trial NCT06842225?
The interventions under investigation include: reduced physical activity (OTHER).
Who is sponsoring clinical trial NCT06842225?
This trial is sponsored by Miami University, which has 6 total clinical trials registered on ClinicalTrials.gov.
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