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NCT06820307 · ClinicalTrials.gov registry record · Phase 1

Evaluation of the Effect of Suzetrigine (SUZ) on the Pharmacokinetics of Oral Contraceptives in Healthy Female Participants

A Phase 1 study, sponsored by Vertex Pharmaceuticals Incorporated.

Completed
Registry status
Phase 1
Development phase
50
Enrollment target

NCT06820307: Completed Phase 1 study, sponsored by Vertex Pharmaceuticals Incorporated.

NCT06820307 is a Phase 1 study that has completed, run by Vertex Pharmaceuticals Incorporated. The registered enrollment target is 50 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06820307, a Phase 1 study, has completed, sponsored by Vertex Pharmaceuticals Incorporated.

COMPLETED
Registry status
Phase 1
Development phase
50 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the effect of SUZ on the pharmacokinetics of oral contraceptives.

Interventions

  • DRUG Suzetrigine
  • DRUG NGM/EE
  • DRUG DRSP/EE

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2025-02-25
Est. Completion 2025-04-29
Phase Phase 1
Vertex Pharmaceuticals Incorporated

191 total trials

What the finished NCT06820307 record still lists

NCT06820307 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% lower).

The record links to 0 conditions, and to 3 interventions - of which Suzetrigine is the first listed.

NCT06820307 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT06820307 about?

NCT06820307 is a clinical study titled "Evaluation of the Effect of Suzetrigine (SUZ) on the Pharmacokinetics of Oral Contraceptives in Healthy Female Participants". The purpose of this study is to evaluate the effect of SUZ on the pharmacokinetics of oral contraceptives.

What is the current status of trial NCT06820307?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 50 participants. The study started on 2025-02-25. Estimated completion is 2025-04-29.

What interventions are being tested in trial NCT06820307?

The interventions under investigation include: Suzetrigine (DRUG), NGM/EE (DRUG), DRSP/EE (DRUG).

Who is sponsoring clinical trial NCT06820307?

This trial is sponsored by Vertex Pharmaceuticals Incorporated, which has 191 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT06820307's enrollment target sits among peer trials

50 973rd of 2000 higher than 984 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06820307, the US trial registry maintained by the National Library of Medicine. NCT06820307 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.