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NCT06815471 · ClinicalTrials.gov registry record · Phase 2

CRF2 Agonist for the Treatment of Worsening Heart Failure

A Phase 2 study of Worsening Heart Failure, sponsored by Corteria Pharmaceuticals.

Recruiting
Registry status
Phase 2
Development phase
300
Enrollment target
20
Study locations

NCT06815471: Recruiting Phase 2 study of Worsening Heart Failure, sponsored by Corteria Pharmaceuticals.

NCT06815471 is a Phase 2 study of Worsening Heart Failure that is actively recruiting participants, run by Corteria Pharmaceuticals. The registered enrollment target is 300 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (126% higher). The trial reports 20 study locations across 6 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06815471, a Phase 2 study of Worsening Heart Failure, is actively recruiting participants, sponsored by Corteria Pharmaceuticals.

RECRUITING
Registry status
Phase 2
Development phase
300 participants
Enrollment target
20
Study locations

Study Summary

This study assesses the effects of the investigational drug COR-1167 in subjects hospitalised due to worsening of heart failure (HF)

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG COR-1167

Study Locations (20)

Other

  • Sdružené zdravotnické zařízení Krnov - Krnov
  • Nemocnice Slaný - Slaný
  • Aleksandre Aladashvili Clinic LLC - Tbilisi
  • LTD "Israeli-Georgian Medical Research Clinic Healthycore" - Tbilisi
  • Acad. G. Chapidze Emergency Cardiology Center LTD, Department of Internal Medicine and Medical Research - Tbilisi
  • Acad. G.Chapidze Emergency Cardiology Center, LTD, Department of Multi-center Clinical Trials - Tbilisi
  • Bokhua Memorial Cardiovascular Center LTD - Tbilisi
  • St. Michael's Hospital LLC - Tbilisi
  • Tbilisi Heart and Vascular Clinic, LTD - Tbilisi
  • Georgian Dutch Hospital - Tbilisi
  • LTD Tbilisi Heart Center - Tbilisi
  • Semmelweis Egyetem, Általános Orvostudományi Kar, Városmajori Szív- és Érgyógyászati Klinika - Budapest
  • Budapesti Uzsoki Utcai Kórház, Kardiológia Osztály - Budapest
  • Pécsi Tudományegyetem, Klinikai Központ, I. sz. Belgyógyászati Klinika - Pécs

North Carolina

  • Cone Health Moses Cone Hospital - Greensboro
  • NC Heart and Vascular Research, LLC - Raleigh

Indiana

  • Indiana University Health Methodist Hospital - Indianapolis

Ohio

  • Ohio State University - Columbus

Oklahoma

  • South Oklahoma Heart Research, LLC - Oklahoma City

Czech Republic

  • Fakultní nemocnice Ostrava - Ostrava

Trial Details

FieldValue
Enrollment Target 300 participants
Start Date 2025-08-07
Est. Completion 2026-12
Phase Phase 2
Corteria Pharmaceuticals

1 total trials

What NCT06815471 shows while recruiting

NCT06815471 is an interventional study that assigns participants to a tested intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (126% higher).

The record links to 1 condition, with Worsening Heart Failure appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT06815471 names 20 study sites across 6 states, led by Other, North Carolina, Indiana.

Frequently Asked Questions

What is clinical trial NCT06815471 about?

NCT06815471 is a clinical study titled "CRF2 Agonist for the Treatment of Worsening Heart Failure". This study assesses the effects of the investigational drug COR-1167 in subjects hospitalised due to worsening of heart failure (HF)

What is the current status of trial NCT06815471?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 300 participants. The study started on 2025-08-07. Estimated completion is 2026-12.

What conditions does trial NCT06815471 study?

This clinical trial studies the following conditions: Worsening Heart Failure.

What interventions are being tested in trial NCT06815471?

The interventions under investigation include: Placebo (DRUG), COR-1167 (DRUG).

Who is sponsoring clinical trial NCT06815471?

This trial is sponsored by Corteria Pharmaceuticals, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06815471 being conducted?

This trial has 20 study locations across Indiana, North Carolina, Ohio, Oklahoma, Czech Republic. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

How this trial's enrollment target compares

Where NCT06815471's enrollment target sits among peer trials

300 167th of 2000 higher than 1,814 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06815471, the US trial registry maintained by the National Library of Medicine. NCT06815471 (mid enrollment · wide site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.