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NCT06814262 · ClinicalTrials.gov registry record · NA
Effect of Clear Aligner Attachment Size on Extrusion of Maxillary Lateral Incisors
A NA study of Orthodontic Appliance Complication, sponsored by Virginia Commonwealth University.
- Recruiting
- Registry status
- NA
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT06814262: Recruiting NA study of Orthodontic Appliance Complication, sponsored by Virginia Commonwealth University.
NCT06814262 is a NA study of Orthodontic Appliance Complication that is actively recruiting participants, run by Virginia Commonwealth University. The registered enrollment target is 40 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06814262, a NA study of Orthodontic Appliance Complication, is actively recruiting participants, sponsored by Virginia Commonwealth University.
- RECRUITING
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
Orthodontic treatment has been revolutionized by clear aligner therapy, offering patients a more esthetic and comfortable alternative to traditional braces. In 1999, Align Technology introduced Invisalign. As Invisalign has increased in popularity and demand over the past two decades, clinical trials have shed light on the efficacy of Invisalign treatment. there have been changes in the Invisalign protocol such as introduction of SmartForce features in 2008, such as optimized attachments as well as the implementation of SmartTrack aligner material in 2011. Compared to conventional fixed orthodontic appliances, Invisalign cannot be adjusted on a visit-to visit basis. If ideal tooth movement has not been achieved after completion of the first sequence of aligners, additional trays, known as refinement trays, are required.
Primary Outcome
The aim of this prospective, randomized controlled trial is to determine which of three different attachment sizes (gingivally beveled 1x1x3 mm, gingivally beveled 1x1x4 mm, or gingivally beveled 1x1x5 mm) offers more predictable extrusion of maxillary lateral incisors in patients treated with clear aligners compared to control.
Conditions Studied
Interventions
- DEVICE Corresponding treatment order in the prescription with Align Technology
- DEVICE Superimposition of final and initial positions of lateral incisors: Predicted model
- DEVICE Superimposition of final and initial positions of lateral incisors: Gingivally beveled 1x1x3mm aligners
- DEVICE Superimposition of final and initial positions of lateral incisors: Gingivally beveled 1x1x4mm aligners
- DEVICE Superimposition of final and initial positions of lateral incisors: Gingivally beveled 1x1x5mm aligners
Study Locations (1)
Virginia
- Virginia Commonwealth University - Richmond
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2025-03-31 |
| Est. Completion | 2026-05 |
| Phase | NA |
What NCT06814262 shows while recruiting
NCT06814262 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Orthodontic Appliance Complication appearing as the primary indexed condition, and to 5 interventions - of which Corresponding treatment order in the prescription with Align Technology is the first listed.
NCT06814262 reports a single indexed study location in Virginia.
Frequently Asked Questions
What is clinical trial NCT06814262 about?
NCT06814262 is a clinical study titled "Effect of Clear Aligner Attachment Size on Extrusion of Maxillary Lateral Incisors". Orthodontic treatment has been revolutionized by clear aligner therapy, offering patients a more esthetic and comfortable alternative to traditional braces. In 1999, Align Technology introduced Invisalign. As Invisalign has increased in popularity and demand over the past two decades, clinical trial...
What is the current status of trial NCT06814262?
This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2025-03-31. Estimated completion is 2026-05.
What conditions does trial NCT06814262 study?
This clinical trial studies the following conditions: Orthodontic Appliance Complication.
What interventions are being tested in trial NCT06814262?
The interventions under investigation include: Corresponding treatment order in the prescription with Align Technology (DEVICE), Superimposition of final and initial positions of lateral incisors: Predicted model (DEVICE), Superimposition of final and initial positions of lateral incisors: Gingivally beveled 1x1x3mm aligners (DEVICE), Superimposition of final and initial positions of lateral incisors: Gingivally beveled 1x1x4mm aligners (DEVICE), Superimposition of final and initial positions of lateral incisors: Gingivally beveled 1x1x5mm aligners (DEVICE).
Who is sponsoring clinical trial NCT06814262?
This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06814262 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06814262's enrollment target sits among peer trials
40 1447th of 2000 higher than 465 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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