Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
Effect of Clear Aligner Attachment Size on Extrusion of Maxillary Lateral Incisors
NCT06814262 · View on ClinicalTrials.gov ↗
Study Summary
Orthodontic treatment has been revolutionized by clear aligner therapy, offering patients a more esthetic and comfortable alternative to traditional braces. In 1999, Align Technology introduced Invisalign. As Invisalign has increased in popularity and demand over the past two decades, clinical trials have shed light on the efficacy of Invisalign treatment. there have been changes in the Invisalign protocol such as introduction of SmartForce features in 2008, such as optimized attachments as well as the implementation of SmartTrack aligner material in 2011. Compared to conventional fixed orthodontic appliances, Invisalign cannot be adjusted on a visit-to visit basis. If ideal tooth movement has not been achieved after completion of the first sequence of aligners, additional trays, known as refinement trays, are required.
Conditions Studied
Interventions
- DEVICE Corresponding treatment order in the prescription with Align Technology
- DEVICE Superimposition of final and initial positions of lateral incisors: Predicted model
- DEVICE Superimposition of final and initial positions of lateral incisors: Gingivally beveled 1x1x3mm aligners
- DEVICE Superimposition of final and initial positions of lateral incisors: Gingivally beveled 1x1x4mm aligners
- DEVICE Superimposition of final and initial positions of lateral incisors: Gingivally beveled 1x1x5mm aligners
Study Locations (1)
Virginia
- Virginia Commonwealth University — Richmond
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2025-03-31 |
| Est. Completion | 2026-05 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06814262
The ClinicalTrials.gov registry entry for NCT06814262 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Virginia Commonwealth University, which has 513 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Orthodontic Appliance Complication appearing as the primary indexed condition, and to 5 interventions — of which Corresponding treatment order in the prescription with Align Technology is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06814262 reports 1 study location spanning 1 distinct geographic area — top geographies include Virginia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06814262 about?
NCT06814262 is a clinical study titled "Effect of Clear Aligner Attachment Size on Extrusion of Maxillary Lateral Incisors". Orthodontic treatment has been revolutionized by clear aligner therapy, offering patients a more esthetic and comfortable alternative to traditional braces. In 1999, Align Technology introduced Invisalign. As Invisalign has increased in popularity and demand over the past two decades, clinical trial...
What is the current status of trial NCT06814262?
This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2025-03-31. Estimated completion is 2026-05.
What conditions does trial NCT06814262 study?
This clinical trial studies the following conditions: Orthodontic Appliance Complication. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06814262?
The interventions under investigation include: Corresponding treatment order in the prescription with Align Technology (DEVICE), Superimposition of final and initial positions of lateral incisors: Predicted model (DEVICE), Superimposition of final and initial positions of lateral incisors: Gingivally beveled 1x1x3mm aligners (DEVICE), Superimposition of final and initial positions of lateral incisors: Gingivally beveled 1x1x4mm aligners (DEVICE), Superimposition of final and initial positions of lateral incisors: Gingivally beveled 1x1x5mm aligners (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06814262?
This trial is sponsored by Virginia Commonwealth University, which has 513 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06814262 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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