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NCT06811246 · ClinicalTrials.gov registry record · Phase 1
A Clinical Study of Islatravir and Its Interaction With Lamivudine (MK-8591-058)
A Phase 1 study, sponsored by Merck Sharp & Dohme.
- Completed
- Registry status
- Phase 1
- Development phase
- 20
- Enrollment target
NCT06811246: Completed Phase 1 study, sponsored by Merck Sharp & Dohme.
NCT06811246 is a Phase 1 study that has completed, run by Merck Sharp & Dohme. The registered enrollment target is 20 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06811246, a Phase 1 study, has completed, sponsored by Merck Sharp & Dohme.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 20 participants
- Enrollment target
Study Summary
The goal of this study is to learn what happens to the medication islatravir (ISL), in a healthy person's body over time--called a pharmacokinetic (PK) study. Researchers want to compare the amount of islatravir in the blood when it is taken alone as a single dose and when it is taken with multiple doses of another medication called lamivudine (3TC).
Primary Outcome
Blood samples will be collected to determine the C168 of ISL-TP
Interventions
- DRUG Lamivudine (3TC)
- DRUG Islatravir (ISL)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2024-02-07 |
| Est. Completion | 2024-07-14 |
| Phase | Phase 1 |
What the finished NCT06811246 record still lists
NCT06811246 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower).
The record links to 0 conditions, and to 2 interventions - of which Lamivudine (3TC) is the first listed.
NCT06811246 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06811246 about?
NCT06811246 is a clinical study titled "A Clinical Study of Islatravir and Its Interaction With Lamivudine (MK-8591-058)". The goal of this study is to learn what happens to the medication islatravir (ISL), in a healthy person's body over time--called a pharmacokinetic (PK) study. Researchers want to compare the amount of islatravir in the blood when it is taken alone as a single dose and when it is taken with multiple ...
What is the current status of trial NCT06811246?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2024-02-07. Estimated completion is 2024-07-14.
What interventions are being tested in trial NCT06811246?
The interventions under investigation include: Lamivudine (3TC) (DRUG), Islatravir (ISL) (DRUG).
Who is sponsoring clinical trial NCT06811246?
This trial is sponsored by Merck Sharp & Dohme, which has 558 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06811246's enrollment target sits among peer trials
20 1629th of 2000 higher than 285 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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