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RECRUITING Phase 4

Safety Study in Subjects ≥ 12 Years of Age With Hereditary Angioedema Switching to Garadacimab

NCT06806657 · View on ClinicalTrials.gov ↗

Study Summary

This study is designed to evaluate the safety after switching to garadacimab from another prophylactic hereditary angioedema (HAE) treatment (marketed kallikrein \[KK\] inhibitor or plasma-derived C1-esterase inhibitor \[pdC1INH\]prophylactic) when administered once monthly for approximately 3 months in participants aged greater than or equal to (\>=) 12 years with HAE.

Conditions Studied

Interventions

  • BIOLOGICAL Garadacimab

Study Locations (10)

Other

  • Clinique Spécialisée en Allergie de la Capitale — Québec
  • HZRM Hämophilie Zentrum Rhein Main GmbH — Frankfurt
  • Hautklinik und Poliklinik der Universitätsklinik Mainz — Mainz

California

  • Donald Levy M.D. — Orange
  • Raffi Tachdjian MD, Inc. — Santa Monica

Arizona

  • Research Solutions of Arizona — Litchfield Park

Arkansas

  • Allergy and Asthma Clinic of Northwest Arkansas — Bentonville

Ohio

  • Bernstein Clinical Research Center, LLC — Cincinnati

Utah

  • Chronicle Bio — West Valley City

Quebec

  • Montreal Clinical Research Institute — Montreal

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2025-03-19
Est. Completion 2026-06-15
Phase Phase 4

Sponsor

CSL Behring

85 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06806657

The ClinicalTrials.gov registry entry for NCT06806657 describes a study currently listed as recruiting. It is categorized as Phase 4, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is CSL Behring, which has 85 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Hereditary Angioedema appearing as the primary indexed condition, and to 1 intervention — of which Garadacimab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06806657 reports 10 study locations spanning 7 distinct geographic areas — top geographies include Other, California, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06806657 about?

NCT06806657 is a clinical study titled "Safety Study in Subjects ≥ 12 Years of Age With Hereditary Angioedema Switching to Garadacimab". This study is designed to evaluate the safety after switching to garadacimab from another prophylactic hereditary angioedema (HAE) treatment (marketed kallikrein \[KK\] inhibitor or plasma-derived C1-esterase inhibitor \[pdC1INH\]prophylactic) when administered once monthly for approximately 3 month...

What is the current status of trial NCT06806657?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 30 participants. The study started on 2025-03-19. Estimated completion is 2026-06-15.

What conditions does trial NCT06806657 study?

This clinical trial studies the following conditions: Hereditary Angioedema. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06806657?

The interventions under investigation include: Garadacimab (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06806657?

This trial is sponsored by CSL Behring, which has 85 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06806657 being conducted?

This trial has 10 study locations across Arizona, Arkansas, California, Ohio, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial