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NCT06793943 · ClinicalTrials.gov registry record · Phase 1

A Study of Interaction of Zasocitinib (TAK-279) With Other Medicines in Healthy Adults

A Phase 1 study, sponsored by Takeda.

Completed
Registry status
Phase 1
Development phase
78
Enrollment target

NCT06793943: Completed Phase 1 study, sponsored by Takeda.

NCT06793943 is a Phase 1 study that has completed, run by Takeda. The registered enrollment target is 78 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (30% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06793943, a Phase 1 study, has completed, sponsored by Takeda.

COMPLETED
Registry status
Phase 1
Development phase
78 participants
Enrollment target

Study Summary

The main aim of this study is to find out how zasocitinib (TAK-279) interacts with other medicines taken by mouth (orally). This will be examined by how the body processes medicines, which is called pharmacokinetics or PK. In this study, other medicines that will be administered together with zasocitinib include a contraceptive (levonorgestrel (LNG) and ethinyl estradiol \[EE\]), a medicine for diabetes (metformin), a medicine used for heart problems (digoxin), and a medicine that blocks the production of stomach acid (esomeprazole). Another aim is to learn about the side effects of zasocitinib and how well it is tolerated when taken alone and together with these other medicines. During the study, participants will need to stay at the clinic for up to 27 days.

Interventions

  • DRUG Metformin
  • DRUG Esomeprazole
  • DRUG Zasocitinib
  • DRUG Digoxin
  • DRUG COC

Trial Details

FieldValue
Enrollment Target 78 participants
Start Date 2025-01-23
Est. Completion 2025-03-30
Phase Phase 1
Takeda

408 total trials

What the finished NCT06793943 record still lists

NCT06793943 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 78 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (30% higher).

The record links to 0 conditions, and to 5 interventions - of which Metformin is the first listed.

NCT06793943 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT06793943 about?

NCT06793943 is a clinical study titled "A Study of Interaction of Zasocitinib (TAK-279) With Other Medicines in Healthy Adults". The main aim of this study is to find out how zasocitinib (TAK-279) interacts with other medicines taken by mouth (orally). This will be examined by how the body processes medicines, which is called pharmacokinetics or PK. In this study, other medicines that will be administered together with zasoci...

What is the current status of trial NCT06793943?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 78 participants. The study started on 2025-01-23. Estimated completion is 2025-03-30.

What interventions are being tested in trial NCT06793943?

The interventions under investigation include: Metformin (DRUG), Esomeprazole (DRUG), Zasocitinib (DRUG), Digoxin (DRUG), COC (DRUG).

Who is sponsoring clinical trial NCT06793943?

This trial is sponsored by Takeda, which has 408 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT06793943's enrollment target sits among peer trials

78 697th of 2000 higher than 1,298 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06793943, the US trial registry maintained by the National Library of Medicine. NCT06793943 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.