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Safety and Tolerability of IPH4502 in Patients With Advanced Solid Tumors
NCT06781983 · View on ClinicalTrials.gov ↗
Study Summary
This is a first-in-human, open-label, multicenter, Phase 1 study to evaluate the safety, tolerability and preliminary efficacy of IPH4502 and to determine the recommended Phase 2 dose (RP2D) in advanced solid tumors that are known to express Nectin-4
Conditions Studied
Interventions
- DRUG IPH4502
Study Locations (7)
Other
- Centre Léon Bérard — Lyon
- Gustave Roussy Cancer Institute — Villejuif
Massachusetts
- Massachusetts General Hospital - Boston — Boston
New Jersey
- John Theurer Cancer Center — Hackensack
New York
- Mount Sinai Tisch Cancer Center — New York
Texas
- NEXT Oncology - Dallas — Dallas
Virginia
- NEXT Oncology - Virginia — Fairfax
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 145 participants |
| Start Date | 2025-01-24 |
| Est. Completion | 2029-04 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06781983
The ClinicalTrials.gov registry entry for NCT06781983 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 145 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Innate Pharma, which has 63 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Advanced or Metastatic Solid Tumors appearing as the primary indexed condition, and to 1 intervention — of which IPH4502 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06781983 reports 7 study locations spanning 6 distinct geographic areas — top geographies include Other, Massachusetts, New Jersey. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06781983 about?
NCT06781983 is a clinical study titled "Safety and Tolerability of IPH4502 in Patients With Advanced Solid Tumors". This is a first-in-human, open-label, multicenter, Phase 1 study to evaluate the safety, tolerability and preliminary efficacy of IPH4502 and to determine the recommended Phase 2 dose (RP2D) in advanced solid tumors that are known to express Nectin-4
What is the current status of trial NCT06781983?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 145 participants. The study started on 2025-01-24. Estimated completion is 2029-04.
What conditions does trial NCT06781983 study?
This clinical trial studies the following conditions: Advanced or Metastatic Solid Tumors. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06781983?
The interventions under investigation include: IPH4502 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06781983?
This trial is sponsored by Innate Pharma, which has 63 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06781983 being conducted?
This trial has 7 study locations across Massachusetts, New Jersey, New York, Texas, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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