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NCT06781775 · ClinicalTrials.gov registry record · Phase 4

GDM: Insulin with or Without Metformin?

A Phase 4 study of Gestational Diabetes, sponsored by University of Virginia.

Recruiting
Registry status
Phase 4
Development phase
130
Enrollment target
1
Study location

NCT06781775 is a Phase 4 study of Gestational Diabetes that is actively recruiting participants, run by University of Virginia. The registered enrollment target is 130 participants, below the 319-participant average among 41 other Gestational Diabetes trials with a reported enrollment target (59% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06781775, a Phase 4 study of Gestational Diabetes, is actively recruiting participants, sponsored by University of Virginia.

RECRUITING
Registry status
Phase 4
Development phase
130 participants
Enrollment target
1
Study location

Study Summary

This will be a randomized trial of patients with gestational diabetes who start hypoglycemic therapy with metformin but eventually require insulin. It will examine whether continuing metformin when adding insulin versus discontinuing metformin when insulin is added is beneficial. The investigators hypothesize that continuing metformin will reduce the needed insulin dosage and improve maternal and neonatal outcomes in these patients.

Conditions Studied

Interventions

  • DRUG Insulin
  • DRUG Metformin + Insulin

Study Locations (1)

Virginia

  • University of Virginia - Charlottesville

Trial Details

FieldValue
Enrollment Target 130 participants
Start Date 2024-12-12
Est. Completion 2027-05-01
Phase Phase 4

Sponsor

University of Virginia

449 total trials

What the Registry Record Tells You About NCT06781775

The ClinicalTrials.gov registry entry for NCT06781775 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 130 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 319-participant average among 41 other Gestational Diabetes trials with a reported enrollment target (59% lower). The listed sponsor is University of Virginia, which has 449 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Gestational Diabetes appearing as the primary indexed condition, and to 2 interventions - of which Insulin is the first listed.

NCT06781775 reports 1 study location spanning 1 distinct geographic area - top geographies include Virginia.

Frequently Asked Questions

What is clinical trial NCT06781775 about?

NCT06781775 is a clinical study titled "GDM: Insulin with or Without Metformin?". This will be a randomized trial of patients with gestational diabetes who start hypoglycemic therapy with metformin but eventually require insulin. It will examine whether continuing metformin when adding insulin versus discontinuing metformin when insulin is added is beneficial. The investigators h...

What is the current status of trial NCT06781775?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 130 participants. The study started on 2024-12-12. Estimated completion is 2027-05-01.

What conditions does trial NCT06781775 study?

This clinical trial studies the following conditions: Gestational Diabetes.

What interventions are being tested in trial NCT06781775?

The interventions under investigation include: Insulin (DRUG), Metformin + Insulin (DRUG).

Who is sponsoring clinical trial NCT06781775?

This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06781775 being conducted?

This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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