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NCT06781775 · ClinicalTrials.gov registry record · Phase 4
GDM: Insulin with or Without Metformin?
A Phase 4 study of Gestational Diabetes, sponsored by University of Virginia.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 130
- Enrollment target
- 1
- Study location
NCT06781775: Recruiting Phase 4 study of Gestational Diabetes, sponsored by University of Virginia.
NCT06781775 is a Phase 4 study of Gestational Diabetes that is actively recruiting participants, run by University of Virginia. The registered enrollment target is 130 participants, below the 319-participant average among 41 other Gestational Diabetes trials with a reported enrollment target (59% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06781775, a Phase 4 study of Gestational Diabetes, is actively recruiting participants, sponsored by University of Virginia.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 130 participants
- Enrollment target
- 1
- Study location
Study Summary
This will be a randomized trial of patients with gestational diabetes who start hypoglycemic therapy with metformin but eventually require insulin. It will examine whether continuing metformin when adding insulin versus discontinuing metformin when insulin is added is beneficial. The investigators hypothesize that continuing metformin will reduce the needed insulin dosage and improve maternal and neonatal outcomes in these patients.
Primary Outcome
Insulin dosage (units per kilogram body weight) at last visit prenatal visit
Conditions Studied
Interventions
- DRUG Insulin
- DRUG Metformin + Insulin
Study Locations (1)
Virginia
- University of Virginia - Charlottesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 130 participants |
| Start Date | 2024-12-12 |
| Est. Completion | 2027-05-01 |
| Phase | Phase 4 |
What NCT06781775 shows while recruiting
NCT06781775 is an interventional study that assigns participants to a tested intervention. The registered 130 participants enrollment target is mid-sized for trials with a published cap, below the 319-participant average among 41 other Gestational Diabetes trials with a reported enrollment target (59% lower).
The record links to 1 condition, with Gestational Diabetes appearing as the primary indexed condition, and to 2 interventions - of which Insulin is the first listed.
NCT06781775 reports a single indexed study location in Virginia.
Frequently Asked Questions
What is clinical trial NCT06781775 about?
NCT06781775 is a clinical study titled "GDM: Insulin with or Without Metformin?". This will be a randomized trial of patients with gestational diabetes who start hypoglycemic therapy with metformin but eventually require insulin. It will examine whether continuing metformin when adding insulin versus discontinuing metformin when insulin is added is beneficial. The investigators h...
What is the current status of trial NCT06781775?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 130 participants. The study started on 2024-12-12. Estimated completion is 2027-05-01.
What conditions does trial NCT06781775 study?
This clinical trial studies the following conditions: Gestational Diabetes.
What interventions are being tested in trial NCT06781775?
The interventions under investigation include: Insulin (DRUG), Metformin + Insulin (DRUG).
Who is sponsoring clinical trial NCT06781775?
This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06781775 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Gestational Diabetes
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06781775's enrollment target sits among peer trials
130 16th of 41 higher than 26 of 41 other Gestational Diabetes trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Gestational Diabetes trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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