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NCT06780306 · ClinicalTrials.gov registry record · Phase 2
A Study in the Treatment of Mild to Moderate Dry Eye Disease Comparing Saline to TTAX03.
A Phase 2 study, sponsored by BioTissue Holdings.
- Completed
- Registry status
- Phase 2
- Development phase
- 74
- Enrollment target
NCT06780306: Completed Phase 2 study, sponsored by BioTissue Holdings.
NCT06780306 is a Phase 2 study that has completed, run by BioTissue Holdings. The registered enrollment target is 74 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (44% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06780306, a Phase 2 study, has completed, sponsored by BioTissue Holdings.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 74 participants
- Enrollment target
Study Summary
The purpose of this randomized, controlled, multicenter study is to evaluate the safety and efficacy of TTAX03 in participants with mild to moderate DED. The primary question it aims to answer is if TTAX03 is safe. The secondary is the effectiveness. Researchers will compare 10mg of TTAX03 reconstituted in 150, 300, or 600 uL saline to the saline control group to look at effectiveness. Participants will be randomized to a treatment group one time and be evaluated at 5 different study visits.
Primary Outcome
Incidence and nature of treatment emergent adverse events (TEAE) between TTAX03 and saline.
Interventions
- BIOLOGICAL TTAX03
- BIOLOGICAL Saline (NaCl 0,9 %) (placebo)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 74 participants |
| Start Date | 2024-12-12 |
| Est. Completion | 2026-01-30 |
| Phase | Phase 2 |
What the finished NCT06780306 record still lists
NCT06780306 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 74 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (44% lower).
The record links to 0 conditions, and to 2 interventions - of which TTAX03 is the first listed.
NCT06780306 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06780306 about?
NCT06780306 is a clinical study titled "A Study in the Treatment of Mild to Moderate Dry Eye Disease Comparing Saline to TTAX03.". The purpose of this randomized, controlled, multicenter study is to evaluate the safety and efficacy of TTAX03 in participants with mild to moderate DED. The primary question it aims to answer is if TTAX03 is safe. The secondary is the effectiveness. Researchers will compare 10mg of TTAX03 reconst...
What is the current status of trial NCT06780306?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 74 participants. The study started on 2024-12-12. Estimated completion is 2026-01-30.
What interventions are being tested in trial NCT06780306?
The interventions under investigation include: TTAX03 (BIOLOGICAL), Saline (NaCl 0,9 %) (placebo) (BIOLOGICAL).
Who is sponsoring clinical trial NCT06780306?
This trial is sponsored by BioTissue Holdings, which has 13 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06780306's enrollment target sits among peer trials
74 920th of 2000 higher than 1,077 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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