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NCT06751355 · ClinicalTrials.gov registry record

Precision Imaging to Evaluate Kaposi Sarcoma (PRIME-KS): A Device Feasibility Trial

A clinical trial of Kaposi Sarcoma, sponsored by Washington University School of Medicine.

Recruiting
Registry status
20
Enrollment target
1
Study location

NCT06751355 is a study of Kaposi Sarcoma that is actively recruiting participants, run by Washington University School of Medicine. The registered enrollment target is 20 participants, below the 101-participant average among 13 other Kaposi Sarcoma trials with a reported enrollment target (80% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06751355, a study of Kaposi Sarcoma, is actively recruiting participants, sponsored by Washington University School of Medicine.

RECRUITING
Registry status
20 participants
Enrollment target
1
Study location

Study Summary

While tremendous progress has been made against HIV, both in preventing the infection and in treating AIDS, the disease it causes, AIDS-related malignancies like Kaposi sarcoma (KS) remain a significant health burden, in both the U.S. and especially the developing world. In many cases, multiple KS lesions develop simultaneously, and may progress and regress independently. Photographs are an essential part of the evaluation for KS, as reflected in their formal usage described in the KS Tumor Assessment Manual of Procedures. However, acquiring a clear, informative photo is not trivial, since anatomy is 3D and conventional imaging is 2D. The importance of accurate, quantitative 3D information is especially pronounced for the treatment of KS because when a tumor responds positively to treatment, the initial change is usually a flattening of the lesion, without any significant change in the projected 2D area. To evaluate the vertical space, along with other characteristics of a KS lesion, we have created an innovative imaging system, SkinScan3D, utilizing new commercial liquid lens technologies and AI based image analysis software, with strategies borrowed from astronomical imaging techniques previously used on NASA space telescopes. In this study, the investigators will develop and demonstrate a protocol for recording measurable 3D parameters, which may be used in a longitudinal study to rigorously monitor therapeutic responses of KS and statistically compare with that of the conventional AMC criteria.

Conditions Studied

Interventions

  • DEVICE SkinScan3D camera

Study Locations (1)

Missouri

  • Washington University School of Medicine - St Louis

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2025-02-25
Est. Completion 2026-05-31

What the Registry Record Tells You About NCT06751355

The ClinicalTrials.gov registry entry for NCT06751355 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 101-participant average among 13 other Kaposi Sarcoma trials with a reported enrollment target (80% lower). The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Kaposi Sarcoma appearing as the primary indexed condition, and to 1 intervention - of which SkinScan3D camera is the first listed.

NCT06751355 reports 1 study location spanning 1 distinct geographic area - top geographies include Missouri.

Frequently Asked Questions

What is clinical trial NCT06751355 about?

NCT06751355 is a clinical study titled "Precision Imaging to Evaluate Kaposi Sarcoma (PRIME-KS): A Device Feasibility Trial". While tremendous progress has been made against HIV, both in preventing the infection and in treating AIDS, the disease it causes, AIDS-related malignancies like Kaposi sarcoma (KS) remain a significant health burden, in both the U.S. and especially the developing world. In many cases, multiple KS l...

What is the current status of trial NCT06751355?

This trial is currently recruiting. The enrollment target is 20 participants. The study started on 2025-02-25. Estimated completion is 2026-05-31.

What conditions does trial NCT06751355 study?

This clinical trial studies the following conditions: Kaposi Sarcoma.

What interventions are being tested in trial NCT06751355?

The interventions under investigation include: SkinScan3D camera (DEVICE).

Who is sponsoring clinical trial NCT06751355?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06751355 being conducted?

This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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