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NCT06751355 · ClinicalTrials.gov registry record
Precision Imaging to Evaluate Kaposi Sarcoma (PRIME-KS): A Device Feasibility Trial
A clinical trial of Kaposi Sarcoma, sponsored by Washington University School of Medicine.
- Recruiting
- Registry status
- 20
- Enrollment target
- 1
- Study location
NCT06751355: Recruiting study of Kaposi Sarcoma, sponsored by Washington University School of Medicine.
NCT06751355 is a study of Kaposi Sarcoma that is actively recruiting participants, run by Washington University School of Medicine. The registered enrollment target is 20 participants, below the 101-participant average among 13 other Kaposi Sarcoma trials with a reported enrollment target (80% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06751355, a study of Kaposi Sarcoma, is actively recruiting participants, sponsored by Washington University School of Medicine.
- RECRUITING
- Registry status
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
While tremendous progress has been made against HIV, both in preventing the infection and in treating AIDS, the disease it causes, AIDS-related malignancies like Kaposi sarcoma (KS) remain a significant health burden, in both the U.S. and especially the developing world. In many cases, multiple KS lesions develop simultaneously, and may progress and regress independently. Photographs are an essential part of the evaluation for KS, as reflected in their formal usage described in the KS Tumor Assessment Manual of Procedures. However, acquiring a clear, informative photo is not trivial, since anatomy is 3D and conventional imaging is 2D. The importance of accurate, quantitative 3D information is especially pronounced for the treatment of KS because when a tumor responds positively to treatment, the initial change is usually a flattening of the lesion, without any significant change in the projected 2D area. To evaluate the vertical space, along with other characteristics of a KS lesion, we have created an innovative imaging system, SkinScan3D, utilizing new commercial liquid lens technologies and AI based image analysis software, with strategies borrowed from astronomical imaging techniques previously used on NASA space telescopes. In this study, the investigators will develop and demonstrate a protocol for recording measurable 3D parameters, which may be used in a longitudinal study to rigorously monitor therapeutic responses of KS and statistically compare with that of the conventional AMC criteria.
Primary Outcome
Feasibility is defined as \> 90% of lesions captured in the conventional imaging procedures are also seen in the SkinScan3D data, and that unique height and volume data is captured by the SkinScan3D for \> 70% of lesions.
Conditions Studied
Interventions
- DEVICE SkinScan3D camera
Study Locations (1)
Missouri
- Washington University School of Medicine - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2025-02-25 |
| Est. Completion | 2026-05-31 |
What NCT06751355 shows while recruiting
NCT06751355 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 101-participant average among 13 other Kaposi Sarcoma trials with a reported enrollment target (80% lower).
The record links to 1 condition, with Kaposi Sarcoma appearing as the primary indexed condition, and to 1 intervention - of which SkinScan3D camera is the first listed.
NCT06751355 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT06751355 about?
NCT06751355 is a clinical study titled "Precision Imaging to Evaluate Kaposi Sarcoma (PRIME-KS): A Device Feasibility Trial". While tremendous progress has been made against HIV, both in preventing the infection and in treating AIDS, the disease it causes, AIDS-related malignancies like Kaposi sarcoma (KS) remain a significant health burden, in both the U.S. and especially the developing world. In many cases, multiple KS l...
What is the current status of trial NCT06751355?
This trial is currently recruiting. The enrollment target is 20 participants. The study started on 2025-02-25. Estimated completion is 2026-05-31.
What conditions does trial NCT06751355 study?
This clinical trial studies the following conditions: Kaposi Sarcoma.
What interventions are being tested in trial NCT06751355?
The interventions under investigation include: SkinScan3D camera (DEVICE).
Who is sponsoring clinical trial NCT06751355?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06751355 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Kaposi Sarcoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06751355's enrollment target sits among peer trials
20 14th of 13 the lowest of 13 other Kaposi Sarcoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Kaposi Sarcoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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