Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT06748209 · ClinicalTrials.gov registry record · Phase 4

Establishing Mobile Transcranial Magnetic Stimulation

A Phase 4 study of Treatment Resistant Major Depression, sponsored by Medical University of South Carolina.

Recruiting
Registry status
Phase 4
Development phase
30
Enrollment target
1
Study location

NCT06748209: Recruiting Phase 4 study of Treatment Resistant Major Depression, sponsored by Medical University of South Carolina.

NCT06748209 is a Phase 4 study of Treatment Resistant Major Depression that is actively recruiting participants, run by Medical University of South Carolina. The registered enrollment target is 30 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT06748209, a Phase 4 study of Treatment Resistant Major Depression, is actively recruiting participants, sponsored by Medical University of South Carolina.

RECRUITING
Registry status
Phase 4
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

In this pilot study, investigators propose to design and create a portable TMS unit, in a van, and then test out delivering TMS in three different locations in South Carolina, all affiliated with MUSC and within 2-hours driving from Charleston, SC. This study would test out this new delivery mode, and provide valuable feasibility, safety, and efficacy lessons for later refinement and potential widespread adoption of mobile TMS as a treatment option, both in our state and across the US.

Primary Outcome

Number of patients with \>50% improvement in Phq-9 scores before and then after 5 days of treatment

Interventions

  • DEVICE Left prefrontal Transcranial Magnetic Stimulation (TMS)
  • DEVICE FDA cleared TMS for treating depression

Study Locations (1)

South Carolina

  • Medical Univerity of South Carolina - Charleston

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2025-05-10
Est. Completion 2028-03-01
Phase Phase 4

What NCT06748209 shows while recruiting

NCT06748209 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (94% lower).

The record links to 1 condition, with Treatment Resistant Major Depression appearing as the primary indexed condition, and to 2 interventions - of which Left prefrontal Transcranial Magnetic Stimulation (TMS) is the first listed.

NCT06748209 reports a single indexed study location in South Carolina.

Frequently Asked Questions

What is clinical trial NCT06748209 about?

NCT06748209 is a clinical study titled "Establishing Mobile Transcranial Magnetic Stimulation". In this pilot study, investigators propose to design and create a portable TMS unit, in a van, and then test out delivering TMS in three different locations in South Carolina, all affiliated with MUSC and within 2-hours driving from Charleston, SC. This study would test out this new delivery mode, a...

What is the current status of trial NCT06748209?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 30 participants. The study started on 2025-05-10. Estimated completion is 2028-03-01.

What conditions does trial NCT06748209 study?

This clinical trial studies the following conditions: Treatment Resistant Major Depression.

What interventions are being tested in trial NCT06748209?

The interventions under investigation include: Left prefrontal Transcranial Magnetic Stimulation (TMS) (DEVICE), FDA cleared TMS for treating depression (DEVICE).

Who is sponsoring clinical trial NCT06748209?

This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06748209 being conducted?

This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

How this trial's enrollment target compares

Where NCT06748209's enrollment target sits among peer trials

30 1552nd of 2000 higher than 368 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00977977 · 30 participants · Phase 2

    Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy

  • NCT01459107 · 30 participants · Phase 2

    Human Upper Extremity Allotransplantation

  • NCT01666080 · 30 participants · NA

    Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)

  • NCT01720836 · 30 participants · Phase 1

    Study of the Immune Response of MUC1 (Mucin1) Peptide Vaccine for Non-small Cell Lung Cancer

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT06748209, the US trial registry maintained by the National Library of Medicine. NCT06748209 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.