Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT06722417 · ClinicalTrials.gov registry record · Phase 1

A Single Dose Study to Assess Adverse Events and How Oral Icalcaprant Moves Through the Body in Healthy Adult Japanese and Han Chinese Participants

A Phase 1 study, sponsored by AbbVie.

Completed
Registry status
Phase 1
Development phase
16
Enrollment target

NCT06722417: Completed Phase 1 study, sponsored by AbbVie.

NCT06722417 is a Phase 1 study that has completed, run by AbbVie. The registered enrollment target is 16 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT06722417, a Phase 1 study, has completed, sponsored by AbbVie.

COMPLETED
Registry status
Phase 1
Development phase
16 participants
Enrollment target

Study Summary

This study will assess the pharmacokinetics, safety, and tolerability of icalcaprant administered orally in healthy adult Japanese and Han Chinese participants.

Primary Outcome

Cmax of Icalcaprant

Interventions

  • DRUG Icalcaprant

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2024-11-26
Est. Completion 2025-01-17
Phase Phase 1
AbbVie

526 total trials

What the finished NCT06722417 record still lists

NCT06722417 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower).

The record links to 0 conditions, and to 1 intervention - of which Icalcaprant is the first listed.

NCT06722417 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT06722417 about?

NCT06722417 is a clinical study titled "A Single Dose Study to Assess Adverse Events and How Oral Icalcaprant Moves Through the Body in Healthy Adult Japanese and Han Chinese Participants". This study will assess the pharmacokinetics, safety, and tolerability of icalcaprant administered orally in healthy adult Japanese and Han Chinese participants.

What is the current status of trial NCT06722417?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2024-11-26. Estimated completion is 2025-01-17.

What interventions are being tested in trial NCT06722417?

The interventions under investigation include: Icalcaprant (DRUG).

Who is sponsoring clinical trial NCT06722417?

This trial is sponsored by AbbVie, which has 526 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT06722417's enrollment target sits among peer trials

16 1786th of 2000 higher than 203 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02422641 · 16 participants · Phase 2

    Prospective Evaluation Of High-Dose Systemic Methotrexate In Patients With Breast Cancer And Leptomeningeal Metastasis

  • NCT02851758 · 16 participants · NA

    Transplantation of Autologously Derived Mitochondria Following Ischemia

  • NCT03291028 · 16 participants

    Analysis of Primary and Metastatic Tumors in Patients With Renal Cell Carcinoma and Urothelial Carcinoma

  • NCT03425526 · 16 participants · Phase 1

    Donor T Cell Therapy in Treating Immunocompromised Patients With Adenovirus-Related Disease

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT06722417, the US trial registry maintained by the National Library of Medicine. NCT06722417 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.