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NCT06718686 · ClinicalTrials.gov registry record · Phase 1

Rifaximin SSD in Dementia Trial

A Phase 1 study of Dementia Alzheimer Type and Dementia Associated With Cerebrovascular Disease, sponsored by Jasmohan Bajaj.

Recruiting
Registry status
Phase 1
Development phase
20
Enrollment target
1
Study location

NCT06718686: Recruiting Phase 1 study of Dementia Alzheimer Type and Dementia Associated With Cerebrovascular Disease, sponsored by Jasmohan Bajaj.

NCT06718686 is a Phase 1 study of Dementia Alzheimer Type and Dementia Associated With Cerebrovascular Disease that is actively recruiting participants, run by Jasmohan Bajaj. The registered enrollment target is 20 participants, below the 73-participant average among 8 other Dementia Alzheimer Type trials with a reported enrollment target (73% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT06718686, a Phase 1 study of Dementia Alzheimer Type and Dementia Associated With Cerebrovascular Disease, is actively recruiting participants, sponsored by Jasmohan Bajaj.

RECRUITING
Registry status
Phase 1
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

Using a new formulation of rifaximin, a non-absorbable antibiotic, to test if it can affect microbes in the gut of patients with dementia favorably.

Primary Outcome

Change in SCFA in stool and serum in rifaximin SSD phase vs placebo phase

Interventions

  • DRUG Placebo
  • DRUG Rifaximin SSD 40 mg IR tablet

Study Locations (1)

Virginia

  • Richmond VA Medical Center - Richmond

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2024-12-30
Est. Completion 2026-05
Phase Phase 1
Jasmohan Bajaj

2 total trials

What NCT06718686 shows while recruiting

NCT06718686 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 73-participant average among 8 other Dementia Alzheimer Type trials with a reported enrollment target (73% lower).

The record links to 2 conditions, with Dementia Alzheimer Type appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT06718686 reports a single indexed study location in Virginia.

Frequently Asked Questions

What is clinical trial NCT06718686 about?

NCT06718686 is a clinical study titled "Rifaximin SSD in Dementia Trial". Using a new formulation of rifaximin, a non-absorbable antibiotic, to test if it can affect microbes in the gut of patients with dementia favorably.

What is the current status of trial NCT06718686?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2024-12-30. Estimated completion is 2026-05.

What conditions does trial NCT06718686 study?

This clinical trial studies the following conditions: Dementia Alzheimer Type, Dementia Associated With Cerebrovascular Disease.

What interventions are being tested in trial NCT06718686?

The interventions under investigation include: Placebo (DRUG), Rifaximin SSD 40 mg IR tablet (DRUG).

Who is sponsoring clinical trial NCT06718686?

This trial is sponsored by Jasmohan Bajaj, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06718686 being conducted?

This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Dementia Alzheimer Type

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06718686's enrollment target sits among peer trials

20 9th of 8 the lowest of 8 other Dementia Alzheimer Type trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Dementia Alzheimer Type trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06718686, the US trial registry maintained by the National Library of Medicine. NCT06718686 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.