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NCT06716749 · ClinicalTrials.gov registry record · Phase 2
Effectiveness of Adding Morphine to Intraosseous Vancomycin for Pain Control in Total Knee Arthroplasty
A Phase 2 study, sponsored by Carilion Clinic.
- Completed
- Registry status
- Phase 2
- Development phase
- 100
- Enrollment target
NCT06716749 is a Phase 2 study that has completed, run by Carilion Clinic. The registered enrollment target is 100 participants.
The verdict
NCT06716749, a Phase 2 study, has completed, sponsored by Carilion Clinic.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 100 participants
- Enrollment target
Study Summary
Study investigators propose to investigate if a bony injection of pain medication during a knee replacement will help pain levels following primary knee replacement surgery. To investigate this, 86 patients will be enrolled. Half of the patients will receive a bony injection of antibiotics with morphine (pain medication) while the other half will receive a bony injection of antibiotics with placebo (no pain medication). Following surgery, patient pain levels and pain medication consumption will be measured. The injection is intraosseous meaning in the bone. The needle pierces the bone and the medication is injected into the bone. The site of injection is on the anterior (front) of the upper portion of the tibia. The medications are Vancomycin (antibiotic) and Morphine (pain medication) which are mixed in separate syringes and then injected. Intraosseous vancomycin is standard of care while intraosseous vancomycin with morphine is also standard of care, depending on operating surgeon.
Interventions
- DRUG Vancomycin
- DRUG Morphine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2024-12-01 |
| Est. Completion | 2025-06-02 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06716749
The ClinicalTrials.gov registry entry for NCT06716749 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Carilion Clinic, which has 45 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Vancomycin is the first listed.
NCT06716749 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT06716749 about?
NCT06716749 is a clinical study titled "Effectiveness of Adding Morphine to Intraosseous Vancomycin for Pain Control in Total Knee Arthroplasty". Study investigators propose to investigate if a bony injection of pain medication during a knee replacement will help pain levels following primary knee replacement surgery. To investigate this, 86 patients will be enrolled. Half of the patients will receive a bony injection of antibiotics with morp...
What is the current status of trial NCT06716749?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 100 participants. The study started on 2024-12-01. Estimated completion is 2025-06-02.
What interventions are being tested in trial NCT06716749?
The interventions under investigation include: Vancomycin (DRUG), Morphine (DRUG).
Who is sponsoring clinical trial NCT06716749?
This trial is sponsored by Carilion Clinic, which has 45 total clinical trials registered on ClinicalTrials.gov.
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