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CardiolRx in Recurrent Pericarditis (MAVERIC Phase-3)
NCT06708299 · View on ClinicalTrials.gov ↗
Study Summary
Multi-center, randomized, double-blind, placebo-controlled, phase-3 Trial. Patients with a history of recurrent pericarditis who are being treated with an IL-1 blocker for at least 12 months, scheduled to be discontinued, will be approached for potential trial participation. Double-blind treatment will be initiated 10 - 16 days prior to the last scheduled dose of the IL-1 blocker and continued for 24 weeks. The objective is to assess whether patients remain free of pericarditis recurrence while receiving CardiolRx.
Conditions Studied
Interventions
- DRUG CardiolRx
Study Locations (20)
New York
- NYU Langone Health — New York
- Columbia University - New York Presbyterian — New York
- Columbia University - New York Presbyterian — New York
- Lenox Hill Hospital — New York
Florida
- Mayo Clinic Florida — Jacksonville
- Mayo Clinic — Jacksonville
Maryland
- Johns Hopkins University — Baltimore
- MedStar Health Institute — Columbia
Minnesota
- Minneapolis Heart Institute — Minneapolis
- Mayo Clinic — Rochester
Virginia
- University of Virginia — Charlottesville
- Virginia Commonwealth University — Richmond
Arizona
- Mayo Clionic Arizona — Phoenix
California
- UCI Health — Irvine
Illinois
- Northwestern University — Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 110 participants |
| Start Date | 2025-04-07 |
| Est. Completion | 2026-10-21 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06708299
The ClinicalTrials.gov registry entry for NCT06708299 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 110 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Cardiol Therapeutics, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Recurrent Pericarditis appearing as the primary indexed condition, and to 1 intervention — of which CardiolRx is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06708299 reports 20 study locations spanning 13 distinct geographic areas — top geographies include New York, Florida, Maryland. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06708299 about?
NCT06708299 is a clinical study titled "CardiolRx in Recurrent Pericarditis (MAVERIC Phase-3)". Multi-center, randomized, double-blind, placebo-controlled, phase-3 Trial. Patients with a history of recurrent pericarditis who are being treated with an IL-1 blocker for at least 12 months, scheduled to be discontinued, will be approached for potential trial participation. Double-blind treatment ...
What is the current status of trial NCT06708299?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 110 participants. The study started on 2025-04-07. Estimated completion is 2026-10-21.
What conditions does trial NCT06708299 study?
This clinical trial studies the following conditions: Recurrent Pericarditis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06708299?
The interventions under investigation include: CardiolRx (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06708299?
This trial is sponsored by Cardiol Therapeutics, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06708299 being conducted?
This trial has 20 study locations across Arizona, California, Florida, Illinois, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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